95 phenotypes from 12 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Latem1(IMPC)Ics/Latem1(IMPC)Ics C57BL/6N-Latem1(IMPC)Ics/Ics	abnormal startle reflex	J:211773
	abnormal vitreous body morphology	J:211773
	increased circulating bilirubin level	J:211773
Lattm1.1Mal/Lattm1.1Mal involves: 129S2/SvPas	abnormal B cell activation	J:77098
	abnormal gamma-delta T cell differentiation	J:77098
	abnormal immune serum protein physiology	J:77098
	abnormal immune system organ morphology	J:77098
	abnormal lymph node germinal center morphology	J:125722
	abnormal lymph node secondary follicle morphology	J:125722
	abnormal lymphocyte morphology	J:77098
	abnormal salivary gland morphology	J:262891
	abnormal spleen periarteriolar lymphoid sheath morphology	J:125722
	abnormal T cell selection	J:77098
	abnormal T cell subpopulation ratio	J:77098
	abnormal T-helper 2 physiology	J:125722
	albuminuria	J:125722
	chronic inflammation	J:77098
	decreased body weight	J:262891
	decreased double-positive T cell number	J:77098
	enlarged lymph nodes	J:77098
	enlarged spleen	J:77098
	glomerulonephritis	J:125722
	increased anti-chromatin antibody level	J:125722
	increased anti-erythrocyte antigen antibody level	J:125722
	increased anti-nuclear antigen antibody level	J:125722
	increased B cell number	J:77098
	increased blood urea nitrogen level	J:125722
	increased CD4-positive, alpha-beta T cell number	J:77098, J:125722
	increased eosinophil cell number	J:77098
	increased IgE level	J:77098, J:125722
	increased IgG1 level	J:77098, J:125722, J:262891
	increased IgM level	J:125722
	increased inflammatory response	J:262891
	increased interferon-gamma secretion	J:77098
	increased interleukin-4 secretion	J:77098
	increased memory T cell number	J:77098
	increased plasma cell number	J:125722
	increased spleen germinal center number	J:125722
	increased spleen weight	J:262891
	increased susceptibility to autoimmune hemolytic anemia	J:125722
	increased T cell proliferation	J:77098
	increased T-helper 2 cell number	J:77098
	kidney inflammation	J:262891
	liver inflammation	J:125722
	lung inflammation	J:125722
	pancreas fibrosis	J:262891
	pancreas inflammation	J:262891
	phlebitis	J:262891
	renal fibrosis	J:262891
	renal glomerular immunoglobulin deposits	J:125722
	salivary gland inflammation	J:262891
	spleen hyperplasia	J:77098
	thymus hypoplasia	J:77098
Lattm1.1Mal/Lattm1.1Mal involves: 129S2/SvPas * C57BL/6	abnormal T cell proliferation	J:131351
	abnormal T-helper 2 physiology	J:131351
Lattm1Bpay/Lattm1Bpay involves: 129S2/SvPas	abnormal platelet aggregation	J:103904
	abnormal T cell differentiation	J:103904
	arrested T cell differentiation	J:103904
	decreased double-negative T cell number	J:103904
	decreased T cell number	J:103904
	decreased thymocyte number	J:103904
	normal immune system phenotype	J:103904
	small thymus	J:103904
Lattm1Les/Lattm1.1Wz involves: C57BL/6	abnormal effector T cell morphology	J:147946
Lattm1Les/Lattm1.1Wz Tg(Cd4-cre)1Cwi/0 involves: C57BL/6 * DBA/2	abnormal effector T cell morphology	J:147946
	abnormal T cell differentiation	J:147946
	abnormal T cell physiology	J:147946
	decreased CD4-positive, alpha-beta T cell number	J:147946
	decreased CD8-positive, alpha-beta T cell number	J:147946
	decreased regulatory T cell number	J:147946
	decreased thymocyte number	J:147946
	increased double-positive T cell number	J:147946
	increased gamma-delta T cell number	J:147946
	small thymus	J:147946
Lattm1Les/Lattm1.2Wz involves: C57BL/6 * FVB/N	absent T cells	J:147946
	arrested T cell differentiation	J:147946
Lattm1Les/Lattm1Les Not Specified	abnormal T cell morphology	J:54059
	arrested T cell differentiation	J:54059, J:116964
	decreased double-negative T cell number	J:54059
	decreased T cell number	J:54059
	decreased thymocyte number	J:54059
	small thymus	J:54059
Lattm2.1Lov/Lattm2.1Lov involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N	abnormal T cell differentiation	J:77695
	decreased T cell number	J:77695
	small thymus	J:77695
Lattm2.1Mal/Lattm2.1Mal involves: 129S2/SvPas	abnormal B cell activation	J:94074
	abnormal B cell differentiation	J:94074
	abnormal gamma-delta T cell differentiation	J:94074
	abnormal immune system organ morphology	J:94074
	abnormal lymphocyte morphology	J:94074
	abnormal lymphopoiesis	J:94074
	abnormal mature gamma-delta T cell morphology	J:94074
	abnormal plasma cell morphology	J:94074
	abnormal spleen morphology	J:94074
	abnormal spleen periarteriolar lymphoid sheath morphology	J:94074
	abnormal spleen white pulp morphology	J:94074
	abnormal T cell activation	J:94074
	abnormal T-helper 2 cell morphology	J:94074
	abnormal thymocyte activation	J:94074
	absent CD4-positive, alpha-beta T cells	J:94074
	absent CD8-positive, alpha-beta T cells	J:94074
	arrested T cell differentiation	J:94074
	decreased double-positive T cell number	J:94074
	enlarged lymph nodes	J:94074
	enlarged spleen	J:94074
	increased B cell number	J:94074
	increased IgE level	J:94074
	increased IgG1 level	J:94074
	increased immunoglobulin level	J:94074
	increased interleukin-4 secretion	J:94074
	increased mature gamma-delta T cell number	J:94074
	premature death	J:94074
	thymus hypoplasia	J:94074
Lattm3.1Mal/Lattm3.1Mal involves: 129S2/SvPas	abnormal gamma-delta T cell differentiation	J:94074
	abnormal lymph node cell ratio	J:94074
	abnormal splenic cell ratio	J:94074
	abnormal thymocyte activation	J:94074
	abnormal thymus cell ratio	J:94074
	absent CD4-positive, alpha-beta T cells	J:94074
	absent CD8-positive, alpha-beta T cells	J:94074
	absent mature gamma-delta T cells	J:94074
	arrested T cell differentiation	J:94074
	decreased double-positive T cell number	J:94074
	decreased T cell number	J:94074
	increased T cell number	J:94074
Lattm4.1Mal/Lattm4.1Mal involves: 129P2/OlaHsd	abnormal gamma-delta T cell differentiation	J:94074
	abnormal lymph node cell ratio	J:94074
	abnormal lymphocyte morphology	J:94074
	abnormal splenic cell ratio	J:94074
	abnormal thrombosis	J:125744
	abnormal thymocyte activation	J:94074
	abnormal thymus cell ratio	J:94074
	absent CD4-positive, alpha-beta T cells	J:94074
	absent CD8-positive, alpha-beta T cells	J:94074
	absent mature gamma-delta T cells	J:94074
	arrested T cell differentiation	J:94074
	decreased double-positive T cell number	J:94074
	decreased platelet aggregation	J:125744
	decreased T cell number	J:94074
Lattm5.1Mal/Lattm5.1Mal involves: C57BL/6	arrested T cell differentiation	J:152363
Lattm9Mal/Lattm9Mal involves: C57BL/6	abnormal B cell number	J:205441
	abnormal immune system morphology	J:205441
	abnormal immune system physiology	J:205441
	abnormal lymphopoiesis	J:205441
	increased T-helper 2 cell number	J:205441