Hhip Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hhip
Hedgehog-interacting protein
MGI:1341847

18 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Hhip^tm1Amc/Hhip⁺ Ptch1^tm1Mps/Ptch1^tm1Mps Tg(Mt1-Ptch1)MT22Mps/0 involves: 129S1/Sv * 129X1/SvJ * FVB	abnormal neural tube morphology	J:94269
	abnormal neuronal precursor cell number	J:94269
	exencephaly	J:94269
	small first pharyngeal arch	J:94269
	spina bifida	J:94269
Hhip^tm1Amc/Hhip^tm1Amc Ptch1^tm1Mps/Ptch1⁺ involves: 129S1/Sv * 129X1/SvJ	abnormal branching involved in pancreas development	J:85472
	abnormal neural tube morphology	J:94269
	abnormal pancreas development	J:85472
	abnormal pulmonary alveolar duct morphology	J:94269
	abnormal stomach glandular epithelium morphology	J:85472
	embryonic lethality, complete penetrance	J:85472
	incomplete rostral neuropore closure	J:94269
	increased embryo size	J:94269
	increased neuronal precursor cell number	J:94269
	small lung	J:85472
Hhip^tm1Amc/Hhip^tm1Amc Ptch1^tm1Mps/Ptch1^tm1Mps Tg(Mt1-Ptch1)MT22Mps/0 involves: 129S1/Sv * 129X1/SvJ * FVB	abnormal neural tube morphology	J:94269
	abnormal neuronal precursor cell number	J:94269
	anophthalmia	J:94269
	embryonic lethality during organogenesis, incomplete penetrance	J:94269
	enlarged first pharyngeal arch	J:94269
	enlarged floor plate	J:94269
	incomplete rostral neuropore closure	J:94269

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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