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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Muc2
mucin 2
MGI:1339364
45 phenotypes from 7 alleles in 8 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Muc2eey/Muc2eey
C57BL/6-Muc2eey
abnormal colon morphology J:194148
abnormal endoplasmic reticulum morphology J:194148
abnormal enterocyte proliferation J:194148
abnormal intestinal goblet cell morphology J:194148
abnormal large intestine crypts of Lieberkuhn morphology J:194148
abnormal mitochondrial crista morphology J:194148
dilated mitochondria J:194148
ileum inflammation J:194148
increased endoplasmic reticulum stress J:194148
increased enterocyte apoptosis J:194148
increased interferon-gamma secretion J:194148
increased interleukin-1 beta secretion J:194148
increased leukocyte cell number J:194148
increased susceptibility to induced colitis J:194148
increased tumor necrosis factor secretion J:194148
melena J:194148
normal neoplasm J:194148
premature death J:194148
rectal prolapse J:194148
Muc2eey/Muc2wnn
C57BL/6-Muc2eey/Muc2wnn
abnormal intestine morphology J:194148
Muc2keny/Muc2keny
C57BL/6JAnu-Muc2keny/Apb
abnormal digestive system physiology J:104190
diarrhea J:104190
enlarged lymph nodes J:104190
Muc2M1Btlr/Muc2+
C57BL/6J-Muc2M1Btlr
increased susceptibility to induced colitis J:150326
Muc2M1Btlr/Muc2M1Btlr
C57BL/6J-Muc2M1Btlr
increased susceptibility to induced colitis J:150326
Muc2m2Btlr/?
C57BL/6J-Muc2m2Btlr
increased susceptibility to induced colitis J:159359
Muc2m3Btlr/Muc2m3Btlr
C57BL/6J-Muc2m3Btlr
increased susceptibility to induced colitis J:254906
Muc2tm1Avel/Muc2tm1Avel
involves: 129P2/OlaHsd * C57BL/6
abnormal cell migration J:75047
abnormal cell physiology J:75047
abnormal enterocyte apoptosis J:75047
abnormal enterocyte morphology J:216831
abnormal enterocyte proliferation J:75047
abnormal intestinal goblet cell morphology J:75047
abnormal intestinal mucosa morphology J:216831
abnormal intestine morphology J:216831
abnormal intestine physiology J:216831
abnormal large intestine crypts of Lieberkuhn morphology J:216831
colitis J:216831
decreased apoptosis J:75047
gastrointestinal hemorrhage J:75047
increased cell proliferation J:75047
increased intestinal adenocarcinoma incidence J:75047
large intestinal inflammation J:216831
Muc2wnn/Muc2+
C57BL/6-Muc2wnn
abnormal intestinal goblet cell morphology J:194148
decreased hematocrit J:194148
increased susceptibility to induced colitis J:194148
rectal hemorrhage J:194148
Muc2wnn/Muc2wnn
C57BL/6-Muc2wnn
abnormal colon morphology J:194148
abnormal digestive system physiology J:194148
abnormal endoplasmic reticulum morphology J:194148
abnormal enterocyte proliferation J:194148
abnormal intestinal absorption J:104190
abnormal intestinal goblet cell morphology J:104190, J:194148
abnormal intestinal mucosa morphology J:194148
abnormal intestine physiology J:194148
abnormal large intestine crypts of Lieberkuhn morphology J:194148
abnormal mitochondrial crista morphology J:194148
colitis J:194148
decreased colon length J:194148
decreased hematocrit J:194148
diarrhea J:104190
dilated mitochondria J:194148
ileum inflammation J:194148
increased circulating triglyceride level J:194148
increased endoplasmic reticulum stress J:194148
increased enterocyte apoptosis J:194148
increased interferon-gamma secretion J:194148
increased interleukin-1 beta secretion J:194148
increased interleukin-13 secretion J:194148
increased leukocyte cell number J:194148
increased lymphocyte cell number J:194148
increased sensitivity to xenobiotic induced morbidity/mortality J:194148
increased susceptibility to induced colitis J:194148
increased susceptibility to weight loss J:194148
increased tumor necrosis factor secretion J:194148
intestinal ulcer J:194148
melena J:194148
normal neoplasm J:194148
premature death J:194148
rectal prolapse J:104190, J:194148

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory