82 phenotypes from 6 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
St14Gt(RST485)Byg/St14+ involves: 129P2/OlaHsd * Black Swiss	impaired skin barrier function	J:108567
St14Gt(RST485)Byg/St14Gt(RST485)Byg involves: 129P2/OlaHsd * Black Swiss	abnormal hard palate morphology	J:108567
	abnormal tongue epithelium morphology	J:108567
St14Gt(XM184)Byg/St14+ involves: 129P2/OlaHsd * Black Swiss	impaired skin barrier function	J:108567
St14Gt(XM184)Byg/St14Gt(XM184)Byg involves: 129P2/OlaHsd * Black Swiss	abnormal corneocyte morphology	J:142708
	abnormal epidermis stratum corneum morphology	J:142708
	abnormal hard palate morphology	J:108567
	abnormal tongue epithelium morphology	J:108567
	absent gastric milk in neonates	J:142708
	neonatal lethality, complete penetrance	J:142708
St14tm1.1(KOMP)Vlcg/St14tm1.1(KOMP)Vlcg C57BL/6N-St14tm1.1(KOMP)Vlcg/MbpMmucd	abnormal embryo size	J:211773
	abnormal eye morphology	J:211773
	abnormal limb bud morphology	J:211773
	abnormal liver size	J:211773
	abnormal placenta size	J:211773
	embryonic growth retardation	J:211773
	pale liver	J:211773
	pale yolk sac	J:211773
	pallor	J:211773
	prenatal lethality prior to heart atrial septation	J:211773
	preweaning lethality, complete penetrance	J:211773
St14tm1Bug/St14tm1Bug involves: 129P2/OlaHsd	abnormal epidermis stratum corneum morphology	J:86715
	abnormal epidermis stratum granulosum morphology	J:86715
	abnormal keratinocyte differentiation	J:86715
	abnormal stratum corneum lipid matrix formation	J:86715
	acanthosis	J:86715
	alopecia	J:86715
	enlarged corneocyte envelope	J:86715
	hyperkeratosis	J:86715
	impaired skin barrier function	J:86715
	impaired stratum corneum desquamation	J:86715
	scaly skin	J:86715
	thick epidermis	J:86715
St14tm1Bug/St14tm1Bug involves: 129P2/OlaHsd * Black Swiss	abnormal corneocyte morphology	J:87125, J:142708
	abnormal epidermis stratum corneum morphology	J:87125
	abnormal hair shaft morphology	J:87125
	abnormal piliary canal morphology	J:87125
	abnormal skin appearance	J:87125
	abnormal snout morphology	J:87125
	abnormal vibrissa follicle morphology	J:87125
	absent gastric milk in neonates	J:87125, J:142708
	absent vibrissae	J:87125
	decreased body length	J:87125
	decreased body weight	J:87125
	decreased double-positive T cell number	J:87125
	decreased hair follicle number	J:87125
	dehydration	J:87125
	dry skin	J:87125
	impaired skin barrier function	J:87125
	increased thymocyte apoptosis	J:87125
	neonatal lethality, complete penetrance	J:142708
	postnatal lethality, complete penetrance	J:87125
	reddish skin	J:87125
	shiny skin	J:87125
	underdeveloped hair follicles	J:87125
	wrinkled skin	J:87125
St14tm2Bug/St14tm2Bug involves: 129P2/OlaHsd	abnormal epidermis stratum corneum morphology	J:86715
	abnormal epidermis stratum granulosum morphology	J:86715, J:153070
	abnormal keratinocyte differentiation	J:86715
	abnormal stratum corneum lipid matrix formation	J:86715
	acanthosis	J:86715
	alopecia	J:86715
	enlarged corneocyte envelope	J:86715
	hyperkeratosis	J:86715
	impaired skin barrier function	J:86715
	impaired stratum corneum desquamation	J:86715
	scaly skin	J:86715
	thick epidermis	J:86715
St14tm2Bug/St14tm3Bug Tg(CAG-cre/Esr1*)5Amc/0 involves: 129P2/OlaHsd * 129S6/SvEvTac * Black Swiss * C57BL/6 * CBA	abnormal enterocyte morphology	J:153070
	abnormal enterocyte physiology	J:153070
	abnormal facial morphology	J:153070
	abnormal hair follicle morphology	J:153070
	abnormal large intestine crypts of Lieberkuhn morphology	J:153070
	abnormal large intestine morphology	J:153070
	absent digestive secretion	J:153070
	alopecia	J:153070
	cachexia	J:153070
	hyperkeratosis	J:153070
	intestinal edema	J:153070
	premature death	J:153070
	scaly skin	J:153070
	skin fibrosis	J:153070
	weight loss	J:153070
St14tm2Bug/St14tm3Bug Tg(MMTV-cre)4Mam/0 involves: 129P2/OlaHsd * 129S6/SvEvTac * Black Swiss * FVB	decreased salivation	J:153070
	normal digestive/alimentary phenotype	J:153070
St14tm2Bug/St14tm3Bug Tg(MMTV-cre)4Mam/0 involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J * FVB/NJ * N:Black Swiss	abnormal chemokine secretion	J:213072
	abnormal cytokine secretion	J:213072
	decreased CD4-positive, alpha-beta T cell number	J:213072
	decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number	J:213072
	decreased CD8-positive, alpha-beta T cell number	J:213072
	decreased regulatory T cell number	J:213072
	decreased salivation	J:213072
	decreased tear production	J:213072
	increased anti-nuclear antigen antibody level	J:213072
	increased autoantibody level	J:213072
	increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number	J:213072
	increased effector memory CD4-positive, alpha-beta T cell number	J:213072
	increased effector memory CD8-positive, alpha-beta T cell number	J:213072
	lacrimal gland inflammation	J:213072
	submandibular gland inflammation	J:213072
St14tm2Bug/St14tm3Bug Tg(Vil1-cre)997Gum/0 involves: 129P2/OlaHsd * 129S6/SvEvTac * Black Swiss * C57BL/6 * SJL	abnormal colon morphology	J:153070
	abnormal enterocyte proliferation	J:153070
	absent digestive secretion	J:153070
	chronic diarrhea	J:153070
	colitis	J:153070
	decreased body size	J:153070
	normal digestive/alimentary phenotype	J:153070
	intestinal edema	J:153070
	megacolon	J:153070
	premature death	J:153070
St14tm3Bug/St14tm3Bug involves: 129S6/SvEvTac	abnormal salivary gland physiology	J:213072
	decreased salivation	J:213072
	normal immune system phenotype	J:213072