Shcbp1 Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Shcbp1
Shc SH2-domain binding protein 1
MGI:1338802

7 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rag1^tm1(cre)Thr/? Shcbp1^{tm1c(EUCOMM)Wtsi}/Shcbp1^{tm1c(EUCOMM)Wtsi} involves: C57BL/6N	normal immune system phenotype	J:212898
Shcbp1^{tm1c(EUCOMM)Wtsi}/Shcbp1^{tm1c(EUCOMM)Wtsi} B6(Cg)-Shcbp1^{tm1c(EUCOMM)Wtsi}/Ravi	no abnormal phenotype detected	J:212898
Shcbp1^{tm1c(EUCOMM)Wtsi}/Shcbp1^{tm1c(EUCOMM)Wtsi} Tg(Lck-cre)1Cwi/? involves: C57BL/6 * DBA/2	decreased susceptibility to experimental autoimmune encephalomyelitis	J:212898
	normal immune system phenotype	J:212898
Shcbp1^{tm1d(EUCOMM)Wtsi}/Shcbp1^{tm1d(EUCOMM)Wtsi} involves: C57BL/6N * FVB/N	decreased B cell number	J:212898
	decreased CD4-positive, alpha-beta T cell number	J:212898
	decreased macrophage cell number	J:212898
	decreased susceptibility to experimental autoimmune encephalomyelitis	J:212898
	decreased T cell number	J:212898
	normal immune system phenotype	J:212898

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23