Irs4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Irs4
insulin receptor substrate 4
MGI:1338009

13 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Irs4^tm1.1Mfw/Y involves: 129S1/Sv * 129X1/SvJ * C57BL/6	normal growth/size/body region phenotype	J:221293
	normal homeostasis/metabolism phenotype	J:221293
	increased circulating glucose level	J:221293
	normal mortality/aging	J:221293
	normal reproductive system phenotype	J:221293
Irs4^tm1Lhd/Y involves: 129S4/SvJae * BALB/c	abnormal fertility/fecundity	J:59964
	decreased litter size	J:59964
	impaired glucose tolerance	J:59964
Irs4^tm1Lhd/Y involves: 129S4/SvJae * C57BL/6	abnormal fertility/fecundity	J:59964
	decreased body weight	J:59964
	decreased circulating glucose level	J:59964
	decreased litter size	J:59964
	impaired glucose tolerance	J:59964
	postnatal growth retardation	J:59964
Irs4^tm1Lhd/Irs4^tm1Lhd involves: 129S4/SvJae * BALB/c	abnormal fertility/fecundity	J:59964
Irs4^tm1Lhd/Irs4^tm1Lhd involves: 129S4/SvJae * BALB/c	decreased litter size	J:59964
Irs4^tm1Lhd/Irs4^tm1Lhd involves: 129S4/SvJae * C57BL/6	abnormal fertility/fecundity	J:59964
	abnormal glucose tolerance	J:59964
	abnormal maternal nurturing	J:59964
	decreased litter size	J:59964
	normal growth/size/body region phenotype	J:59964
	normal homeostasis/metabolism phenotype	J:59964

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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