About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Rnf7
ring finger protein 7
MGI:1337096
28 phenotypes from 3 alleles in 5 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Rnf7Gt(XE423)Byg/Rnf7Gt(XE423)Byg
involves: 129P2/OlaHsd
increased apoptosis J:164457
increased cellular sensitivity to ionizing radiation J:164457
oxidative stress J:164457
Rnf7Gt(XE423)Byg/Rnf7Gt(XE423)Byg
involves: 129P2/OlaHsd * C57BL/6
abnormal cell cycle J:178926
abnormal cell differentiation J:178926
abnormal visceral yolk sac blood island morphology J:178926
abnormal vitelline vasculature morphology J:178926
decreased angiogenesis J:178926
decreased cell proliferation J:178926
embryonic growth retardation J:178926
embryonic lethality during organogenesis, complete penetrance J:178926
increased embryonic tissue cell apoptosis J:178926
increased spinal cord apoptosis J:178926
pericardial edema J:178926
Rnf7tm1a(EUCOMM)Wtsi/Rnf7+
Not Specified
abnormal response to tactile stimuli J:165965
decreased circulating chloride level J:165965
decreased circulating triglyceride level J:165965
increased circulating chloride level J:165965
Rnf7tm1c(EUCOMM)Wtsi/Rnf7tm1c(EUCOMM)Wtsi
involves: C57BL/6N
no abnormal phenotype detected J:205551
Rnf7tm1c(EUCOMM)Wtsi/Rnf7tm1c(EUCOMM)Wtsi
involves: C57BL/6N
abnormal neuronal migration J:205551
Rnf7tm1c(EUCOMM)Wtsi/Rnf7tm1c(EUCOMM)Wtsi
Tg(Nes-cre)1Kln/0
involves: C57BL/6 * C57BL/6N * SJL
abnormal cerebellar layer morphology J:205551
decreased cerebellar granule cell precursor proliferation J:205551
delaminated Purkinje cell layer J:205551
ectopic Purkinje cell J:205551
enlarged brain ventricles J:205551
hydrocephaly J:205551
postnatal growth retardation J:205551
small cerebellum J:205551

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory