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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tsix
X (inactive)-specific transcript, opposite strand
MGI:1336196
16 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tsixtm1.1Awu/Tsix+
Tg(CAG-EGFP)50Osb/0
Gt(ROSA)26Sortm1(rtTA)Awu/Gt(ROSA)26Sortm1(rtTA)Awu
involves: 129P2/OlaHsd * 129S4/SvJae * C3H/HeSlc * C57BL/6J * C57BL/6Slc 		abnormal capillary morphology J:174672
abnormal DNA methylation J:174672
abnormal dosage compensation, by inactivation of X chromosome J:174672
abnormal imprinting J:174672
abnormal placenta labyrinth morphology J:174672
abnormal trophoblast giant cell morphology J:174672
abnormal trophoblast layer morphology J:174672
absent placental labyrinth J:174672
absent spongiotrophoblast J:174672
decreased capillary density J:174672
embryonic growth retardation J:174672
increased trophoblast giant cell number J:174672
small placenta J:174672
Tsixtm1.1Awu/Y
Tg(CAG-EGFP)50Osb/0
Gt(ROSA)26Sortm1(rtTA)Awu/Gt(ROSA)26Sortm1(rtTA)Awu
involves: 129P2/OlaHsd * 129S4/SvJae * C3H/HeSlc * C57BL/6J * C57BL/6Slc 		no abnormal phenotype detected J:174672
Tsixtm1.1Awu/Tsixtm1.1Awu
Tg(CAG-EGFP)50Osb/0
Gt(ROSA)26Sortm1(rtTA)Awu/Gt(ROSA)26Sortm1(rtTA)Awu
involves: 129P2/OlaHsd * 129S4/SvJae * C3H/HeSlc * C57BL/6J * C57BL/6Slc 		no abnormal phenotype detected J:174672
Tsixtm1Enl/Tsix+
Xisttm1Jae/Xist+
involves: 129S4/SvJae 		decreased embryo size J:68136
Tsixtm1Enl/Tsix+
Xisttm1Sado/Xist+
involves: 129S4/SvJae 		embryonic lethality between implantation and somite formation, complete penetrance J:99399
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory