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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Dclk1
doublecortin-like kinase 1
MGI:1330861
36 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
ApcMin/Apc+
Dclk1tm1.1(cre/ERT2)Seno/Dclk1+
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sortm1(HBEGF)Awai
involves: 129S4/SvJaeSor * C57BL/6 		abnormal tumor morphology J:193873
normal digestive/alimentary phenotype J:193873
normal endocrine/exocrine gland phenotype J:193873
ApcMin/Apc+
Dclk1tm1.1(cre/ERT2)Seno/Dclk1tm1.1(cre/ERT2)Seno
involves: C57BL/6 		intestine polyps J:193873
Ctnnb1tm1Mmt/Ctnnb1+
Dclk1tm1.1(cre/ERT2)Seno/Dclk1+
involves: 129X1/SvJ * C57BL/6 		normal neoplasm J:193873
Dclk1tm1.1Jgg/Dclk1+
Dcxtm1Caw/Y
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6 		abnormal corpus callosum morphology J:105300
abnormal neuron morphology J:105300
decreased anterior commissure size J:105300
Dclk1tm1.1Jgg/Dclk1+
Dcxtm1Caw/Dcxtm1Caw
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6 		absent corpus callosum J:105300
Dclk1tm1.1Jgg/Dclk1tm1.1Jgg
Dcxtm1Caw/Y
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6 		abnormal anterior commissure morphology J:105300
abnormal stratification in cerebral cortex J:105300
absent corpus callosum J:105300
postnatal lethality, complete penetrance J:105300
Dclk1tm1.1Jgg/Dclk1tm1.1Jgg
Dcxtm1Caw/Dcx+
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6 		abnormal anterior commissure morphology J:105300
abnormal stratification in cerebral cortex J:105300
absent corpus callosum J:105300
Dclk1tm1.1Jgg/Dclk1tm1.1Jgg
Dcxtm1Caw/Dcxtm1Caw
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6 		abnormal brain commissure morphology J:105300
abnormal neuron morphology J:105300
abnormal stratification in cerebral cortex J:105300
absent anterior commissure J:105300
absent corpus callosum J:105300
absent hippocampal commissure J:105300
postnatal lethality, complete penetrance J:105300
Dclk1tm1Caw/Dclk1+
Dcxtm1Caw/Dcx+
involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6J 		reduced female fertility J:105301
Dclk1tm1Caw/Dclk1+
Dcxtm1Caw/Y
involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6J 		abnormal brain morphology J:105301
absent corpus callosum J:105301
enlarged lateral ventricles J:105301
postnatal lethality J:105301
Dclk1tm1Caw/Dclk1tm1Caw
Dcxtm1Caw/Y
involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6J 		abnormal anterior commissure morphology J:105301
abnormal brain internal capsule morphology J:105301
abnormal brain morphology J:105301
abnormal brainstem morphology J:105301
abnormal cerebellar foliation J:105301
abnormal cerebral cortex morphology J:105301
abnormal corpus callosum morphology J:105301
abnormal dentate gyrus morphology J:105301
abnormal entorhinal cortex morphology J:105301
abnormal hippocampal commissure morphology J:105301
abnormal hippocampus layer morphology J:105301
abnormal hippocampus morphology J:105301
abnormal stratification in cerebral cortex J:105301
abnormal striatum morphology J:105301
abnormal temporal lobe morphology J:105301
abnormal thalamus morphology J:105301
absent brain internal capsule J:105301
decreased corpus callosum size J:105301
postnatal lethality, incomplete penetrance J:105301
small cerebellum J:105301
thin cerebral cortex J:105301
Dclk1tm1Caw/Dclk1tm1Caw
Dcxtm1Caw/Dcx+
involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6J 		reduced female fertility J:105301
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory