68 phenotypes from 5 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dyrk1aem1Kzy/Dyrk1a+ C57BL/6J-Dyrk1aem1Kzy	abnormal cerebral hemisphere morphology	J:259596
	abnormal long-term spatial reference memory	J:259596
	abnormal midbrain size	J:259596
	abnormal vocalization	J:259596
	cognitive inflexibility	J:259596
	decreased aggression towards mice	J:259596
	decreased body weight	J:259596
	decreased brain weight	J:259596
	decreased social investigation	J:259596
	decreased vertical activity	J:259596
	decreased vocalization	J:259596
	environmentally induced seizures	J:259596
	impaired spatial learning	J:259596
Dyrk1aGt(XQ0369)Wtsi/Dyrk1a+ involves: 129/Sv * 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6	transmission ratio distortion	J:224899
Dyrk1aGt(XQ0369)Wtsi/Dyrk1aGt(XQ0369)Wtsi involves: 129/Sv * 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6	embryonic lethality, complete penetrance	J:224899
Dyrk1atm1Jdc/Dyrk1atm1Jdc Tg(Mx1-cre)1Cgn/0 involves: 129/Sv * C57BL/6J * C57BL/6NTac * CBA/J	abnormal cell cycle	J:223138
	decreased B cell number	J:223138
	decreased double-positive T cell number	J:223138
	decreased immature B cell number	J:223138
	decreased mature B cell number	J:223138
	decreased pre-B cell number	J:223138
	decreased thymocyte number	J:223138
	increased T cell apoptosis	J:223138
Dyrk1atm1Mla/Dyrk1a+ involves: 129P2/OlaHsd	abnormal brain size	J:182294
	abnormal dentate gyrus morphology	J:182294
	abnormal somatosensory cortex morphology	J:182294
	abnormal thalamus morphology	J:182294
	decreased hippocampus volume	J:182294
Dyrk1atm1Mla/Dyrk1a+ involves: 129P2/OlaHsd * C57BL/6	abnormal cerebral cortex pyramidal cell morphology	J:102616
	abnormal premotor cortex morphology	J:102616
	decreased body length	J:78597
	decreased body size	J:78597
	decreased body weight	J:78597
	decreased brain size	J:78597
	decreased brain weight	J:78597
	decreased heart weight	J:78597
	decreased hindbrain size	J:78597
	decreased liver weight	J:78597
	decreased midbrain size	J:78597
	decreased superior colliculus size	J:78597
	microcephaly	J:102616
	postnatal lethality, incomplete penetrance	J:78597
	small tectum	J:78597
Dyrk1atm1Mla/Dyrk1atm1Mla involves: 129P2/OlaHsd * C57BL/6	abnormal nervous system development	J:78597
	decreased embryo size	J:78597
	embryonic growth retardation	J:78597
	embryonic lethality during organogenesis, incomplete penetrance	J:78597
Tg(Dyrk1a)189N3Yah/0 B6.129P2-Tg(Dyrk1a)189N3Yah/Yah	abnormal circulating androgen level	J:324151
	abnormal dentate gyrus morphology	J:182294
	abnormal enzyme/coenzyme level	J:324151
	abnormal hippocampus molecular cell layer	J:182294
	abnormal hippocampus morphology	J:182294
	abnormal hippocampus stratum oriens morphology	J:182294
	abnormal hormone level	J:324151
	abnormal lateral ventricle morphology	J:182294
	abnormal seminiferous tubule morphology	J:324151
	abnormal somatosensory cortex morphology	J:182294
	abnormal spermatogonia morphology	J:324151
	abnormal thalamus morphology	J:182294
	abnormal third ventricle morphology	J:182294
	arrest of spermatogenesis	J:324151
	decreased body length	J:182294
	decreased body weight	J:182294
	decreased circulating follicle stimulating hormone level	J:324151
	decreased circulating gonadotropin level	J:324151
	decreased circulating luteinizing hormone level	J:324151
	decreased circulating testosterone level	J:324151
	decreased testis weight	J:324151
	increased brain size	J:182294
	increased brain weight	J:182294
	lethality, incomplete penetrance	J:182294
	oligozoospermia	J:324151
	postnatal growth retardation	J:182294
	reduced male fertility	J:324151
	shortened head	J:182294