Abcb7tm1Mdf/Abcb7+
Edil3Tg(Sox2-cre)1Amc/Edil3+
either: B6.Cg-Edil3Tg(Sox2-cre)1Amc Abcb7tm1Mdf or (involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * CBA)
|
normal
mortality/aging |
J:106838
|
Abcb7tm1Mdf/Y
Edil3Tg(Sox2-cre)1Amc/Edil3+
either: B6.Cg-Edil3Tg(Sox2-cre)1Amc Abcb7tm1Mdf or (involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * CBA)
|
embryonic lethality between somite formation and embryo turning, complete penetrance |
J:106838
|
Adgrg6em2Jlp/Adgrg6em2Jlp
Edil3Tg(Sox2-cre)1Amc/Edil3+
Gt(ROSA)26Sortm1(ADGRG6)Jlp/Gt(ROSA)26Sor+
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCrl * CBA
|
embryonic lethality during organogenesis, complete penetrance |
J:315981
|
|
lethality throughout fetal growth and development, incomplete penetrance |
J:315981
|
|
normal
nervous system phenotype |
J:315981
|
Adgrg6em3Jlp/Adgrg6em3Jlp
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: C57BL/6 * CBA
|
decreased body size |
J:315981
|
|
embryonic lethality during organogenesis, complete penetrance |
J:315981
|
|
joint contracture |
J:315981
|
|
lethality throughout fetal growth and development, incomplete penetrance |
J:315981
|
|
small heart |
J:315981
|
Ankmy2tm1a(EUCOMM)Hmgu/Ankmy2tm1a(EUCOMM)Hmgu
Edil3Tg(Sox2-cre)1Amc/0
involves: C57BL/6 * C57BL/6N * CBA
|
abnormal embryonic neuroepithelial layer differentiation |
J:297055
|
|
embryonic lethality between somite formation and embryo turning, complete penetrance |
J:297055
|
Arap3tm1.1Sve/Arap3tm1.2Sve
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129P2/OlaHsd * BALB/cJ * C57BL/6 * CBA * SJL
|
abnormal placenta labyrinth morphology |
J:185401
|
|
abnormal placenta vasculature |
J:185401
|
|
decreased embryo size |
J:185401
|
|
decreased placental labyrinth size |
J:185401
|
|
embryonic growth arrest |
J:185401
|
|
embryonic lethality during organogenesis, complete penetrance |
J:185401
|
|
excessive folding of visceral yolk sac |
J:185401
|
|
pale yolk sac |
J:185401
|
|
pallor |
J:185401
|
Arhgef7tm1c(EUCOMM)Wtsi/Arhgef7tm1c(EUCOMM)Wtsi
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: C57BL/6N * CBA
|
normal
embryo phenotype |
J:217373
|
Casz1tm1.1Flc/Casz1tm1.1Flc
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * CBA * SJL
|
abnormal heart development |
J:221324
|
|
embryonic lethality during organogenesis, complete penetrance |
J:221324
|
|
heart hypoplasia |
J:221324
|
|
thin ventricular wall |
J:221324
|
|
ventricular septal defect |
J:221324
|
Cdx2tm1Fbe/Cdx2tm2Fbe
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA
|
caudal body truncation |
J:179732
|
Chd1tm1c(KOMP)Rsan/Chd1tm1c(KOMP)Rsan
Edil3Tg(Sox2-cre)1Amc/?
involves: 129P2/OlaHsd * C57BL/6J * CBA
|
embryonic lethality, complete penetrance |
J:217689
|
Chd3tm1.1Cya/Chd3tm1.1Cya
Edil3Tg(Sox2-cre)1Amc/0
involves: C57BL/6 * C57BL/6J * CBA
|
embryonic lethality, incomplete penetrance |
J:294633
|
|
normal
reproductive system phenotype |
J:294633
|
Cited2tm1Bha/Cited2tm2Bha
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129 * C57BL/6 * CBA * SJL
|
abnormal heart left ventricle morphology |
J:137951
|
|
abnormal inferior vena cava morphology |
J:137951
|
|
absent adrenal gland |
J:137951
|
|
absent coronary sinus |
J:137951
|
|
common atrioventricular valve |
J:137951
|
|
dextrocardia |
J:137951
|
|
double outlet right ventricle |
J:137951
|
|
exencephaly |
J:137951
|
|
lethality throughout fetal growth and development, incomplete penetrance |
J:137951
|
|
ostium primum atrial septal defect |
J:137951
|
|
postnatal lethality, complete penetrance |
J:137951
|
|
right aortic arch |
J:137951
|
|
right atrial isomerism |
J:137951
|
|
right pulmonary isomerism |
J:137951
|
|
transposition of great arteries |
J:137951
|
|
ventricular septal defect |
J:137951
|
Commd9tm1c(KOMP)Wtsi/Commd9tm1c(KOMP)Wtsi
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: C57BL/6N
|
prenatal lethality, complete penetrance |
J:230747
|
Ctnnb1tm2Kem/Ctnnb1tm2.1Kem
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CBA
|
abnormal embryonic tissue morphology |
J:187739
|
|
prenatal lethality, complete penetrance |
J:187739
|
Ctnnb1tm2Kem/Ctnnb1tm2.1Kem
Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sortm1.1(Ctnnb1)Kem
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CBA
|
abnormal embryonic tissue morphology |
J:187739
|
|
abnormal germ layer development |
J:187739
|
|
failure to gastrulate |
J:187739
|
|
prenatal lethality, complete penetrance |
J:187739
|
Ctsdtm1.1Thre/Ctsdtm1.1Thre
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: C57BL/6 * C57BL/6N * CBA * SJL
|
astrocytosis |
J:227618
|
|
decreased body weight |
J:227618
|
|
decreased double-positive T cell number |
J:227618
|
|
decreased small intestinal villus height |
J:227618
|
|
gliosis |
J:227618
|
|
microgliosis |
J:227618
|
|
neuron degeneration |
J:227618
|
|
premature death |
J:227618
|
|
small intestinal villus atrophy |
J:227618
|
|
thymus atrophy |
J:227618
|
|
weight loss |
J:227618
|
Cul4btm1.1Pz/Cul4b+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129 * C57BL/6 * C57BL/6J * CBA
|
normal
mortality/aging |
J:199210
|
Cul4btm1.1Pz/Y
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129 * C57BL/6 * C57BL/6J * CBA
|
no abnormal phenotype detected |
J:199210
|
Cul4btm1Swl/Y
Edil3Tg(Sox2-cre)1Amc/Edil3+
B6.Cg-Edil3Tg(Sox2-cre)1Amc Cul4btm1Swl
|
abnormal dendrite morphology |
J:187403
|
|
abnormal dendritic spine morphology |
J:187403
|
|
abnormal spatial learning |
J:187403
|
|
decreased neuron number |
J:187403
|
|
impaired spatial working memory |
J:187403
|
|
increased susceptibility to pharmacologically induced seizures |
J:187403
|
Dab2tm2.1Xxx/Dab2tm2.2Xxx
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 * CBA
|
normal
embryo phenotype |
J:205046
|
|
increased circulating cholesterol level |
J:205046
|
|
increased circulating LDL cholesterol level |
J:205046
|
|
normal
mortality/aging |
J:205046
|
Dag1tm1Kcam/Dag1tm2.1Kcam
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
|
abnormal axon fasciculation |
J:194150
|
|
abnormal axon guidance |
J:194150
|
|
abnormal basement membrane morphology |
J:194150
|
|
abnormal spinal cord dorsal column morphology |
J:194150
|
|
abnormal spinal cord ventral commissure morphology |
J:194150
|
|
radial glial endfoot detachment |
J:194150
|
Ddx3xtm1.1Lyou/Ddx3x+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129 * C57BL/6 * CBA
|
no abnormal phenotype detected |
J:231798
|
Ddx3xtm1.1Lyou/Y
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129 * C57BL/6 * CBA
|
abnormal allantois morphology |
J:231798
|
|
abnormal brain development |
J:231798
|
|
abnormal cell cycle |
J:231798
|
|
abnormal cell physiology |
J:231798
|
|
abnormal developmental patterning |
J:231798
|
|
abnormal embryo turning |
J:231798
|
|
abnormal head fold morphology |
J:231798
|
|
abnormal myocardial trabeculae morphology |
J:231798
|
|
abnormal neural tube closure |
J:231798
|
|
embryonic growth retardation |
J:231798
|
|
embryonic lethality prior to tooth bud stage |
J:231798
|
|
failure of chorioallantoic fusion |
J:231798
|
|
increased embryonic tissue cell apoptosis |
J:231798
|
|
increased mitotic index |
J:231798
|
|
microcephaly |
J:231798
|
|
pericardial effusion |
J:231798
|
|
preweaning lethality, complete penetrance |
J:231798
|
|
small allantois |
J:231798
|
Dicer1tm1Bdh/Dicer1tm1Bdh
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129 * C57BL/6 * CBA
|
spina bifida |
J:244791
|
Disp1icb/Disp1icb
Shhtm1Amc/Shhtm5Amc
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129/Sv * C57BL/6J * SWR
|
abnormal frontonasal prominence morphology |
J:94270
|
|
perinatal lethality, complete penetrance |
J:94270
|
Disp1tm1Pab/Disp1tm1Pab
Shhtm2Chg/Shh+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
|
abnormal digit morphology |
J:109101
|
|
perinatal lethality, complete penetrance |
J:109101
|
|
preaxial polydactyly |
J:109101
|
Dph1tm1.1Cmch/Dph1tm1.1Cmch
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J * CBA
|
abnormal tongue position |
J:214744
|
|
absent palatine bone |
J:214744
|
|
cleft palate |
J:214744
|
|
edema |
J:214744
|
|
fetal growth retardation |
J:214744
|
|
mandible hypoplasia |
J:214744
|
|
neonatal lethality, complete penetrance |
J:214744
|
|
palatal shelves fail to meet at midline |
J:214744
|
|
pallor |
J:214744
|
|
short mandible |
J:214744
|
|
small cranium |
J:214744
|
E2f7tm1Gle/E2f7tm1Gle
E2f8tm1Gle/E2f8tm1Gle
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S6/SvEvTac * C57BL/6 * SJL
|
abnormal embryonic tissue morphology |
J:183999
|
|
abnormal respiratory system morphology |
J:183999
|
|
normal
embryo phenotype |
J:183999
|
|
neonatal lethality |
J:183999
|
Edil3Tg(Sox2-cre)1Amc/Edil3+
Wnt7atm1Amc/Wnt7atm1Amc
Wnt7btm1Parr/Wnt7btm2Amc
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
|
abnormal blood-brain barrier function |
J:142352
|
|
abnormal vasculogenesis |
J:142352
|
|
embryonic lethality during organogenesis, complete penetrance |
J:142352
|
|
intracranial hemorrhage |
J:142352
|
|
spinal hemorrhage |
J:142352
|
Edil3Tg(Sox2-cre)1Amc/Edil3+
Tgif1tm1Caw/Tgif1tm1Caw
Tgif2tm1Dwot/Tgif2tm1Dwot
involves: 129S/SvEv * C57BL/6 * C57BL/6J * CBA
|
abnormal cephalic neural fold morphology |
J:183402
|
|
abnormal direction of heart looping |
J:157256
|
|
abnormal forebrain development |
J:183402
|
|
abnormal forebrain morphology |
J:183402
|
|
abnormal heart looping |
J:157256
|
|
abnormal left-right axis patterning |
J:157256
|
|
abnormal olfactory epithelium morphology |
J:183402
|
|
abnormal optic vesicle formation |
J:183402
|
|
abnormal primitive streak elongation |
J:157256
|
|
cyclopia |
J:183402
|
|
decreased embryonic neuroepithelial cell proliferation |
J:183402
|
|
decreased embryonic neuroepithelium thickness |
J:183402
|
|
decreased forebrain size |
J:183402
|
|
embryonic lethality during organogenesis, complete penetrance |
J:157256
|
|
embryonic lethality during organogenesis, incomplete penetrance |
J:183402
|
|
failure of heart looping |
J:157256
|
|
heterotaxia |
J:183402
|
|
incomplete rostral neuropore closure |
J:183402
|
|
increased apoptosis |
J:183402
|
|
proboscis |
J:183402
|
Edil3tm1Tq/Edil3tm1Tq
Itgaltm1Bll/Itgaltm1Bll
involves: 129 * C57BL/6
|
abnormal cellular extravasation |
J:141063
|
|
abnormal neutrophil physiology |
J:141063
|
Eef1a1tm1Tcrl/Eef1a1+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S6/SvEvTac * C57BL/6 * CBA
|
holoprosencephaly |
J:225273
|
|
lethality throughout fetal growth and development, incomplete penetrance |
J:225273
|
|
open neural tube |
J:225273
|
|
postnatal lethality, complete penetrance |
J:225273
|
|
spina bifida |
J:225273
|
Elavl1tm1Dkon/Elavl1tm1Dkon
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129P2/OlaHsd * C57BL/6 * CBA
|
abnormal craniofacial bone morphology |
J:149149
|
|
abnormal lung development |
J:149149
|
|
abnormal spleen development |
J:149149
|
|
abnormal vertebrae development |
J:149149
|
|
absent spleen |
J:149149
|
|
delayed endochondral bone ossification |
J:149149
|
|
lethality throughout fetal growth and development, complete penetrance |
J:149149
|
|
midline facial cleft |
J:149149
|
|
short limbs |
J:149149
|
|
small limb buds |
J:149149
|
|
split xiphoid process |
J:149149
|
|
syndactyly |
J:149149
|
|
synostosis |
J:149149
|
Enpp2tm1Vart/Enpp2tm1Vart
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: C57BL/6 * CBA
|
embryonic lethality |
J:159118
|
Eomestm1Rob/Eomes+
Nodaltm1Rob/Nodal+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S/SvEv * C57BL/6 * CBA
|
prenatal lethality |
J:131055
|
|
rostral body truncation |
J:131055
|
Eomestm1Rob/Eomestm1.1Rob
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S/SvEv * C57BL/6 * CBA
|
abnormal embryonic epiblast morphology |
J:131055
|
|
abnormal primitive streak morphology |
J:131055
|
|
absent mesoderm |
J:131055
|
Eomestm1Rob/Eomestm1.1Rob
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S/SvEv * 129S4/SvJae * C57BL/6 * CBA
|
abnormal endoderm development |
J:131055
|
|
abnormal visceral endoderm morphology |
J:131055
|
Eomestm1Rob/Eomestm2.1Rob
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S/SvEv * C57BL/6 * CBA
|
abnormal embryonic epiblast morphology |
J:154785
|
|
abnormal primitive streak morphology |
J:154785
|
|
failure to gastrulate |
J:154785
|
Erbb3tm1.1Dwt/Erbb3tm2.1Dwt
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S6/SvEvTac * C57BL/6 * CBA
|
preweaning lethality, complete penetrance |
J:152703
|
Esrrbtm1.1Nat/Esrrbtm1.2Nat
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S6/SvEvTac * C57BL/6 * CBA * SJL
|
abnormal scala media morphology |
J:124941
|
|
abnormal semicircular canal ampulla morphology |
J:124941
|
|
abnormal semicircular canal morphology |
J:124941
|
|
absent startle reflex |
J:124941
|
|
circling |
J:124941
|
|
decreased endolymph production |
J:124941
|
|
head bobbing |
J:124941
|
|
increased or absent threshold for auditory brainstem response |
J:124941
|
|
small scala media |
J:124941
|
Evc2tm2.1Mis/Evc2tm2.1Mis
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129X1/SvJ * C57BL/6 * CBA
|
disproportionate dwarf |
J:226455
|
Fam20ctm1.1Cqi/Fam20ctm1.1Cqi
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S6/SvEvTac * C57BL/6 * CBA
|
abnormal chondrocyte differentiation |
J:185208
|
|
abnormal circulating protein level |
J:185208
|
|
abnormal limb long bone morphology |
J:185208
|
|
abnormal long bone diaphysis morphology |
J:185208
|
|
abnormal long bone epiphyseal plate morphology |
J:185208
|
|
abnormal long bone epiphyseal plate proliferative zone |
J:185208
|
|
abnormal osteocyte morphology |
J:185208
|
|
abnormal skeleton morphology |
J:185208
|
|
abnormal vertebral column morphology |
J:185208
|
|
abnormal vitamin D level |
J:185208
|
|
decreased body size |
J:185208
|
|
decreased body weight |
J:185208
|
|
decreased bone mineral density |
J:185208
|
|
decreased bone mineralization |
J:185208
|
|
decreased chondrocyte apoptosis |
J:185208
|
|
decreased chondrocyte proliferation |
J:185208
|
|
decreased circulating phosphate level |
J:185208
|
|
decreased compact bone thickness |
J:185208
|
|
delayed bone ossification |
J:185208
|
|
delayed cranial suture closure |
J:185208
|
|
delayed endochondral bone ossification |
J:185208
|
|
female infertility |
J:185208
|
|
flat face |
J:185208
|
|
fragile skeleton |
J:185208
|
|
impaired osteoblast differentiation |
J:185208
|
|
increased circulating parathyroid hormone level |
J:185208
|
|
increased width of hypertrophic chondrocyte zone |
J:185208
|
|
male infertility |
J:185208
|
|
osteomalacia |
J:185208
|
|
postnatal growth retardation |
J:185208
|
|
rickets |
J:185208
|
|
short snout |
J:185208
|
|
small cranium |
J:185208
|
Fnip1m1Btlr/Fnip1m1Btlr
Prkag2tm1.1Geno/Prkag2tm1.1Geno
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129 * C57BL/6 * C57BL/6J * CBA
|
normal
cardiovascular system phenotype |
J:256296
|
Foxp2tm1Sfis/Foxp2tm1.2Sfis
Edil3Tg(Sox2-cre)1Amc/?
involves: C57BL/6 * CBA * SJL
|
decreased body weight |
J:125023
|
|
delayed eyelid opening |
J:125023
|
|
impaired righting response |
J:125023
|
|
lethality at weaning, complete penetrance |
J:125023
|
|
reduced cerebellar foliation |
J:125023
|
|
small cerebellum |
J:125023
|
Fzd4tm1Nat/Fzd4+
Igs1tm2(CAG-Bgeo,-Ndp,-EGFP)Nat/Igs1tm2(CAG-Bgeo,-Ndp,-EGFP)Nat
Edil3Tg(Sox2-cre)1Amc/?
involves: 129 * C57BL/6 * CBA
|
abnormal angiogenesis |
J:154020
|
|
abnormal descending aorta morphology |
J:154020
|
|
embryonic growth retardation |
J:154020
|
|
embryonic lethality, incomplete penetrance |
J:154020
|
Fzd4tm1Nat/Fzd4tm1Nat
Igs1tm2(CAG-Bgeo,-Ndp,-EGFP)Nat/Igs1tm2(CAG-Bgeo,-Ndp,-EGFP)Nat
Edil3Tg(Sox2-cre)1Amc/?
involves: 129 * C57BL/6 * CBA
|
normal
cardiovascular system phenotype |
J:154020
|
|
normal
growth/size/body region phenotype |
J:154020
|
|
normal
mortality/aging |
J:154020
|
Fzd5tm1Nat/Fzd5tm2Nat
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * SJL
|
abnormal thalamus morphology |
J:136390
|
|
decreased body size |
J:136390
|
|
decreased body weight |
J:136390
|
|
impaired coordination |
J:136390
|
|
retina degeneration |
J:136390
|
Fzr1tm1Mama/Fzr1tm1.1Mama
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: BALB/cJ * C57BL/6 * SJL
|
normal
embryo phenotype |
J:137456
|
|
normal
mortality/aging |
J:137456
|
Fzr1tm1Mama/Fzr1tm1Mama
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: C57BL/6 * CBA * SJL
|
normal
embryo phenotype |
J:137456
|
|
normal
mortality/aging |
J:137456
|
Gli3tm1Alj/Gli3+
Tgif1tm1Caw/Tgif1tm1Caw
Tgif2tm1Dwot/Tgif2tm1Dwot
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6J * CBA
|
abnormal cephalic neural fold morphology |
J:183402
|
|
abnormal forebrain development |
J:183402
|
|
abnormal olfactory epithelium morphology |
J:183402
|
|
decreased embryonic neuroepithelial cell proliferation |
J:183402
|
|
exencephaly |
J:183402
|
Gt(ROSA)26Sortm1(Wnk1)Clhu/Gt(ROSA)26Sor+
Wnk1Gt(OST38262)Lex/Wnk1Gt(OST38262)Lex
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S5/SvEvBrd * C57BL/6 * CBA
|
embryonic lethality during organogenesis |
J:152906
|
Gt(ROSA)26Sortm1.1(DUX4*)Plj/Gt(ROSA)26Sor+
Edil3Tg(Sox2-cre)1Amc/0
involves: C57BL/6 * CBA
|
embryonic lethality, complete penetrance |
J:256652
|
Gt(ROSA)26Sortm3(Snai2)Jhai/Gt(ROSA)26Sor+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCr * CBA
|
embryonic lethality |
J:194078
|
|
hemorrhage |
J:194078
|
|
pallor |
J:194078
|
Gt(ROSA)26Sortm4(Snai1)Jhai/Gt(ROSA)26Sor+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCr * CBA
|
abnormal embryo development |
J:194078
|
|
embryonic lethality during organogenesis, complete penetrance |
J:194078
|
Gt(ROSA)26Sortm5(CAG-Mdm4,-EGFP)Jhai/Gt(ROSA)26Sor+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCr * CBA
|
no abnormal phenotype detected |
J:194078
|
Gt(ROSA)26Sortm6(Vegfa*)Jhai/Gt(ROSA)26Sor+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCr * CBA
|
embryonic lethality |
J:194078
|
Gt(ROSA)26Sortm8(Aifm1)Jhai/Gt(ROSA)26Sor+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCr * CBA
|
normal
mortality/aging |
J:194078
|
Gt(ROSA)26Sortm9(Aifm1*)Jhai/Gt(ROSA)26Sor+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCr * CBA
|
normal
mortality/aging |
J:194078
|
Gt(ROSA)26Sortm10(Gata2)Jhai/Gt(ROSA)26Sor+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCr * CBA
|
embryonic lethality |
J:194078
|
Gt(ROSA)26Sortm11(Gata3)Jhai/Gt(ROSA)26Sor+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCr * CBA
|
normal
mortality/aging |
J:194078
|
Gt(ROSA)26Sortm14Jhai/Gt(ROSA)26Sor+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCr * CBA
|
normal
mortality/aging |
J:194078
|
Gt(ROSA)26Sortm16Jhai/Gt(ROSA)26Sor+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCr * CBA
|
normal
cellular phenotype |
J:195147
|
Hcfc1tm1Lwh/Hcfc1+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: C57BL/6 * CBA
|
abnormal embryo morphology |
J:231596
|
|
abnormal extraembryonic tissue morphology |
J:231596
|
|
decreased body length |
J:231596
|
|
decreased cell proliferation |
J:231596
|
|
decreased embryo size |
J:231596
|
|
decreased lean body mass |
J:231596
|
|
embryonic lethality prior to organogenesis |
J:231596
|
|
embryonic lethality, complete penetrance |
J:231596
|
|
increased apoptosis |
J:231596
|
Hcfc1tm1Lwh/Y
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: C57BL/6 * CBA
|
decreased embryo size |
J:231596
|
|
embryonic lethality prior to organogenesis |
J:231596
|
|
embryonic lethality, complete penetrance |
J:231596
|
Hcfc1tm1Lwh/Hcfc1tm1Lwh
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: C57BL/6 * CBA
|
abnormal embryo morphology |
J:231596
|
|
abnormal extraembryonic tissue morphology |
J:231596
|
|
decreased cell proliferation |
J:231596
|
|
decreased embryo size |
J:231596
|
|
embryonic lethality prior to organogenesis |
J:231596
|
|
embryonic lethality, complete penetrance |
J:231596
|
|
increased apoptosis |
J:231596
|
Igs1tm2(CAG-Bgeo,-Ndp,-EGFP)Nat/Igs1tm2(CAG-Bgeo,-Ndp,-EGFP)Nat
Edil3Tg(Sox2-cre)1Amc/?
involves: 129 * C57BL/6 * CBA
|
abnormal angiogenesis |
J:154020
|
|
abnormal aorta smooth muscle morphology |
J:154020
|
|
embryonic growth retardation |
J:154020
|
|
prenatal lethality, complete penetrance |
J:154020
|
Igs1tm11(CAG-Bgeo,-Edn2)Nat/Igs1+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
|
abnormal vascular development |
J:201133
|
|
embryonic growth retardation |
J:201133
|
|
enlarged heart |
J:201133
|
|
internal hemorrhage |
J:201133
|
|
open neural tube |
J:201133
|
|
prenatal lethality |
J:201133
|
Kdm6atm1c(EUCOMM)Wtsi/Y
Edil3Tg(Sox2-cre)1Amc/Edil3+
either: (involves: C57BL/6 * CBA * CD-1) or (involves: 129 * C57BL/6 * CBA * CD-1)
|
normal
mortality/aging |
J:201868
|
Kdm6atm1c(EUCOMM)Wtsi/Kdm6atm1c(EUCOMM)Wtsi
Edil3Tg(Sox2-cre)1Amc/Edil3+
either: (involves: C57BL/6 * CBA * CD-1) or (involves: 129 * C57BL/6 * CBA * CD-1)
|
lethality throughout fetal growth and development, complete penetrance |
J:201868
|
Lama1tm1.1Arhi/Lama1tm1.2Arhi
Edil3Tg(Sox2-cre)1Amc/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
abnormal Bergmann glial cell morphology |
J:184432
|
|
abnormal brain meninges morphology |
J:184432
|
|
abnormal brain pia mater morphology |
J:184432
|
|
abnormal cerebellar foliation |
J:184432
|
|
abnormal cerebellar granule layer morphology |
J:184432
|
|
abnormal cerebellar Purkinje cell layer |
J:184432
|
|
abnormal cerebellum morphology |
J:184432
|
|
abnormal Purkinje cell dendrite morphology |
J:184432
|
|
abnormal radial glial cell morphology |
J:184432
|
|
impaired coordination |
J:184432
|
|
limb grasping |
J:184432
|
|
normal
mortality/aging |
J:184432
|
|
short stride length |
J:184432
|
|
small cerebellum |
J:184432
|
Lama1tm1Olf/Lama1tm1Olf
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S2/SvPas * C57BL/6J * CBA * CD-1 * Swiss Webster
|
abnormal Muller cell morphology |
J:160722
|
|
abnormal ocular fundus morphology |
J:160722
|
|
abnormal retina blood vessel morphology |
J:160722
|
|
abnormal retina blood vessel pattern |
J:160722
|
|
abnormal retina inner limiting membrane morphology |
J:160722
|
|
abnormal retina neuronal layer morphology |
J:160722
|
|
abnormal retina vasculature morphology |
J:160722
|
|
decreased birth weight |
J:160722
|
|
macrophthalmia |
J:160722
|
|
normal
mortality/aging |
J:160722
|
|
persistence of hyaloid vascular system |
J:160722
|
|
normal
reproductive system phenotype |
J:160722
|
|
retina outer nuclear layer degeneration |
J:160722
|
|
retina spots |
J:160722
|
|
thin retina inner nuclear layer |
J:160722
|
|
thin retina inner plexiform layer |
J:160722
|
|
vitreal fibroplasia |
J:160722
|
Lhx1tm1Bhr/Lhx1tm2.1Rob
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S/SvEv * C57BL/6 * C57BL/6N * CBA
|
abnormal endoderm development |
J:226614
|
|
abnormal heart looping |
J:226614
|
|
abnormal heart morphology |
J:226614
|
|
abnormal nervous system development |
J:226614
|
|
abnormal primitive node morphology |
J:226614
|
|
cardia bifida |
J:226614
|
|
cellular necrosis |
J:226614
|
|
embryonic growth retardation |
J:226614
|
|
enlarged pericardium |
J:226614
|
Lrp5tm1Kry/Lrp5tm1Kry
Igs1tm2(CAG-Bgeo,-Ndp,-EGFP)Nat/Igs1tm2(CAG-Bgeo,-Ndp,-EGFP)Nat
Edil3Tg(Sox2-cre)1Amc/?
involves: 129 * C57BL/6 * CBA
|
abnormal angiogenesis |
J:154020
|
|
abnormal descending aorta morphology |
J:154020
|
|
embryonic growth retardation |
J:154020
|
|
embryonic lethality, incomplete penetrance |
J:154020
|
Map2k1tm1Bacc/Map2k1tm1.1Bacc
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129P2/OlaHsd * C57BL/6 * CBA
|
no abnormal phenotype detected |
J:199705
|
Map2k1tm1Chrn/Map2k1tm1.1Chrn
Edil3Tg(Sox2-cre)1Amc/?
involves: 129S/SvEv * C57BL/6 * CBA * FVB/N
|
normal
reproductive system phenotype |
J:112223
|
Mapk11tm1Jsca/Mapk11+
Mapk14tm2Nbr/Mapk14tm2Nbr
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129P2/OlaHsd * C57BL/6 * CBA
|
primary sex reversal |
J:191096
|
Mapk11tm1Jsca/Mapk11tm1Jsca
Mapk14tm2Nbr/Mapk14tm2Nbr
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129P2/OlaHsd * C57BL/6 * CBA
|
abnormal fetal cardiomyocyte proliferation |
J:176023
|
|
abnormal liver morphology |
J:176023
|
|
abnormal neuron proliferation |
J:176023
|
|
exencephaly |
J:176023
|
|
increased hepatocyte apoptosis |
J:176023
|
|
lethality throughout fetal growth and development, complete penetrance |
J:176023
|
|
primary sex reversal |
J:191096
|
|
small liver |
J:176023
|
|
spina bifida |
J:176023
|
|
ventricular septal defect |
J:176023
|
Mapk11tm1Jsca/Mapk11tm1Jsca
Mapk14tm2Nbr/Mapk14tm3.1(Mapk11)Nbr
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129P2/OlaHsd * C57BL/6 * CBA
|
normal
nervous system phenotype |
J:176023
|
|
postnatal lethality, complete penetrance |
J:176023
|
|
ventricular septal defect |
J:176023
|
Mapk14tm2Nbr/Mapk14tm3.1(Mapk11)Nbr
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: C57BL/6 * CBA
|
postnatal lethality, incomplete penetrance |
J:176023
|
Myctm2.1Atp/Myctm2.1Atp
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129P2/OlaHsd * C57BL/6 * CBA
|
abnormal common myeloid progenitor cell morphology |
J:137630
|
|
abnormal proerythroblast morphology |
J:137630
|
|
normal
cardiovascular system phenotype |
J:137630
|
|
decreased embryo size |
J:137630
|
|
decreased erythroid progenitor cell number |
J:137630
|
|
embryonic lethality during organogenesis, complete penetrance |
J:137630
|
|
impaired hematopoiesis |
J:137630
|
|
liver hypoplasia |
J:137630
|
|
pale yolk sac |
J:137630
|
Nodaltm1Rob/Nodal+
Edil3Tg(Sox2-cre)1Amc/Edil3+
Tgif1tm1Caw/Tgif1tm1Caw
Tgif2tm1Dwot/Tgif2tm1Dwot
involves: 129S/SvEv * C57BL/6 * C57BL/6J * CBA
|
abnormal embryonic neuroepithelium morphology |
J:183402
|
|
abnormal forebrain development |
J:183402
|
|
abnormal left-right axis patterning |
J:157256
|
|
normal
cardiovascular system phenotype |
J:157256
|
|
decreased forebrain size |
J:183402
|
|
embryonic growth retardation |
J:183402
|
|
holoprosencephaly |
J:183402
|
|
rostral body truncation |
J:183402
|
Nodaltm1Rob/Nodaltm5Rob
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S/SvEv * C57BL/6
|
abnormal developmental patterning |
J:93140
|
|
abnormal distal visceral endoderm morphology |
J:93140
|
|
abnormal germ layer development |
J:93140
|
|
absent mesoderm |
J:93140
|
Nsdhltm1.1Hrm/Nsdhl+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6N * CBA
|
abnormal hair growth |
J:220990
|
|
abnormal skeleton morphology |
J:220990
|
|
decreased body size |
J:220990
|
|
hyperkeratosis |
J:220990
|
Nsdhltm1.1Hrm/Y
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6N * CBA
|
postnatal growth retardation |
J:220990
|
Nuggctm1Diaz/Nuggctm1Diaz
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: C57BL/6 * C57BL/6J * CBA
|
abnormal somatic hypermutation frequency |
J:190402
|
|
normal
immune system phenotype |
J:190402
|
Orc1tm1.1Gle/Orc1tm1.2Gle
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: C57BL/6 * CBA * SJL
|
embryonic lethality, complete penetrance |
J:272584
|
Pak4tm2.1Amin/Pak4tm2.2Amin
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S2/SvPas * C57BL/6 * CBA * FVB/N
|
abnormal placenta labyrinth morphology |
J:152821
|
|
abnormal visceral yolk sac morphology |
J:152821
|
|
embryonic growth retardation |
J:152821
|
|
preweaning lethality, complete penetrance |
J:152821
|
Pdgfrbtm12(Pdgfrb)Sor/Pdgfrb+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S4/SvJae * C57BL/6 * CBA
|
no abnormal phenotype detected |
J:173602
|
Pdgfrbtm13(Pdgfrb)Sor/Pdgfrb+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S4/SvJae * C57BL/6 * CBA
|
increased aorta wall thickness |
J:173602
|
|
postnatal growth retardation |
J:173602
|
|
postnatal lethality, complete penetrance |
J:173602
|
Pdgfrbtm14(Pdgfrb)Sor/Pdgfrb+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S4/SvJaeSor * C57BL/6 * CBA
|
abnormal ascending aorta morphology |
J:173602
|
|
abnormal hypodermis fat layer morphology |
J:173602
|
|
abnormal inguinal fat pad morphology |
J:173602
|
|
abnormal mesenteric fat pad morphology |
J:173602
|
|
abnormal white adipose tissue morphology |
J:173602
|
|
abnormal white fat cell differentation |
J:173602
|
|
normal
adipose tissue phenotype |
J:173602
|
|
increased white fat cell number |
J:173602
|
|
postnatal growth retardation |
J:173602
|
|
postnatal lethality, complete penetrance |
J:173602
|
Pnkptm1.1Pmc/Pnkptm1.1Pmc
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S1/Sv * C57BL/6 * CBA
|
embryonic lethality, complete penetrance |
J:226703
|
Porcntm1.1Lcm/Porcn+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
|
abnormal autopod morphology |
J:173672
|
|
abnormal hair follicle development |
J:173672
|
|
abnormal tail morphology |
J:173672
|
|
absent ulna |
J:173672
|
|
caudal body truncation |
J:173672
|
|
cleft palate |
J:173672
|
|
decreased body size |
J:173672
|
|
hairless |
J:173672
|
|
normal
integument phenotype |
J:173672
|
|
omphalocele |
J:173672
|
|
perinatal lethality, complete penetrance |
J:173672
|
|
short tail |
J:173672
|
|
sternum hypoplasia |
J:173672
|
|
thin dermal layer |
J:173672
|
Porcntm1.1Lcm/Y
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
|
abnormal mesoderm development |
J:173672
|
|
lethality throughout fetal growth and development, complete penetrance |
J:173672
|
Prdm15tm1c(EUCOMM)Wtsi/Prdm15tm1c(EUCOMM)Wtsi
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: C57BL/6J * C57BL/6N
|
abnormal brain morphology |
J:285408
|
|
decreased embryo size |
J:285408
|
|
prenatal lethality, complete penetrance |
J:285408
|
Prickle1tm1.2Asw/Prickle1tm1.3Asw
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: C57BL/6 * CBA
|
abnormal hair follicle development |
J:213772
|
|
abnormal hair follicle orientation |
J:213772
|
Prickle1tm1.3Asw/Prickle1tm1.3Asw
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: C57BL/6 * CBA
|
postnatal lethality, complete penetrance |
J:213772
|
Prkag2tm1.1Geno/Prkag2tm1.1Geno
Edil3Tg(Sox2-cre)1Amc/Edil3+
B6.Cg-Prkag2tm1.1Geno Edil3Tg(Sox2-cre)1Amc
|
abnormal sinoatrial node conduction |
J:256296
|
|
increased heart rate |
J:256296
|
Psip1tm1Eng/Psip1tm1Eng
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S6/SvEvTac * C57BL/6 * CBA
|
abnormal cell physiology |
J:177408
|
Ptentm1Ppp/Pten+
Rac1tm1Tyb/Rac1tm2Tyb
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S/Sv * C3H * C57BL/6 * CBA
|
abnormal apoptosis |
J:173526
|
|
abnormal embryo development |
J:173526
|
Rac1tm1Tyb/Rac1tm2Tyb
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S4/SvJae * C3H * C57BL/6 * CBA
|
abnormal cell adhesion |
J:173526
|
|
abnormal developmental patterning |
J:173526
|
|
abnormal mesoderm development |
J:173526
|
|
abnormal neural tube closure |
J:173526
|
|
abnormal notochordal plate morphology |
J:173526
|
|
abnormal primitive node morphology |
J:173526
|
|
abnormal primitive streak morphology |
J:173526
|
|
cardia bifida |
J:173526
|
|
decreased cell proliferation |
J:173526
|
|
decreased embryo size |
J:173526
|
|
impaired somite development |
J:173526
|
|
increased embryonic tissue cell apoptosis |
J:173526
|
|
prenatal lethality, complete penetrance |
J:166095
|
Sall4tm2Tre/Sall4tm2.1Tre
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * CD-1
|
embryonic growth arrest |
J:115635
|
|
embryonic lethality between implantation and somite formation, complete penetrance |
J:115635
|
Shhtm1Chg/Shhtm2Chg
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
|
abnormal carpal bone morphology |
J:109101
|
|
abnormal digit morphology |
J:109101
|
|
abnormal tarsal bone morphology |
J:109101
|
|
perinatal lethality |
J:125109
|
Shhtm2Chg/Shh+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
|
abnormal choroid plexus morphology |
J:125109
|
|
abnormal corpus callosum morphology |
J:125109
|
|
abnormal embryonic/fetal subventricular zone morphology |
J:125109
|
|
abnormal hippocampus development |
J:125109
|
|
abnormal lateral ganglionic eminence morphology |
J:125109
|
|
abnormal maxillary shelf morphology |
J:125109
|
|
abnormal medial ganglionic eminence morphology |
J:125109
|
|
abnormal neurocranium morphology |
J:125109
|
|
abnormal telencephalon development |
J:125109
|
|
abnormal telencephalon morphology |
J:125109
|
|
absent olfactory bulb |
J:125109
|
|
cleft secondary palate |
J:125109
|
|
enlarged brain ventricles |
J:125109
|
|
holoprosencephaly |
J:125109
|
|
increased forebrain size |
J:125109
|
|
increased midbrain size |
J:125109
|
|
palatal shelves fail to meet at midline |
J:125109
|
|
perinatal lethality, complete penetrance |
J:125109
|
|
polydactyly |
J:109101
|
Slc13a4tm1c(EUCOMM)Wtsi/Slc13a4tm1d(EUCOMM)Wtsi
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: C57BL/6 * CBA
|
normal
embryo phenotype |
J:239786
|
|
lethality throughout fetal growth and development, complete penetrance |
J:239786
|
|
normal
mortality/aging |
J:239786
|
Smad2tm1Rob/Smad2tm2Rob
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S/SvEv * C57BL/6 * CBA * CD-1
|
abnormal anterior definitive endoderm morphology |
J:84300
|
|
abnormal heart looping |
J:84300
|
|
abnormal rostral-caudal axis patterning |
J:84300
|
|
absent forebrain |
J:84300
|
|
absent midbrain |
J:84300
|
|
enlarged pericardium |
J:84300
|
|
pericardial edema |
J:84300
|
|
truncated foregut |
J:84300
|
Smad2tm1Rob/Smad2tm2Rob
Smad3tm1Xfw/Smad3+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129/Sv * 129S/SvEv * C57BL/6 * CBA * CD-1
|
abnormal heart development |
J:84300
|
|
absent foregut |
J:84300
|
|
fused somites |
J:84300
|
|
rostral body truncation |
J:84300
|
Smad4tm1Rob/Smad4tm1.1Rob
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S/SvEv * CD-1
|
abnormal allantois morphology |
J:92066
|
|
abnormal dorsal-ventral axis patterning |
J:92066
|
|
abnormal hindbrain development |
J:92066
|
|
abnormal rhombomere morphology |
J:92066
|
|
abnormal rostral-caudal axis patterning |
J:92066
|
|
absent foregut |
J:92066
|
|
absent hindgut |
J:92066
|
|
absent primordial germ cells |
J:92066
|
|
embryonic lethality during organogenesis, complete penetrance |
J:92066
|
|
fused somites |
J:92066
|
Sppl3tm1Itl/Sppl3tm1Itl
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S/SvEv * C57BL/6 * CBA
|
decreased birth body size |
J:280182
|
|
neonatal lethality, incomplete penetrance |
J:280182
|
|
postnatal lethality, incomplete penetrance |
J:280182
|
Strip1tm1b(KOMP)Wtsi/Strip1tm1c(KOMP)Wtsi
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: C57BL/6N * CBA * FVB/NJ * SJL
|
abnormal head fold morphology |
J:251816
|
|
abnormal mesoderm development |
J:251816
|
|
cardia bifida |
J:251816
|
|
normal
embryo phenotype |
J:251816
|
|
short rostral-caudal axis |
J:251816
|
Tlk2tm1.1Strc/Tlk2tm1.2Strc
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S/SvEv * C3H * C57BL/6
|
no abnormal phenotype detected |
J:268910
|
Trim28tm1.1Ipc/Trim28tm1.2Ipc
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S2/SvPas * C57BL/6 * CBA
|
abnormal digestive system development |
J:178936
|
|
abnormal lateral plate mesoderm morphology |
J:178936
|
|
abnormal vitelline vasculature morphology |
J:178936
|
|
normal
embryo phenotype |
J:178936
|
|
embryonic growth arrest |
J:178936
|
|
short rostral-caudal axis |
J:178936
|
|
wavy neural tube |
J:178936
|
Trim33tm1.1Los/Trim33tm1.2Los
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S2/SvPas * C57BL/6 * CBA * SJL
|
abnormal brain development |
J:163858
|
|
abnormal endoderm development |
J:163858
|
|
abnormal mesendoderm development |
J:163858
|
|
abnormal primitive node morphology |
J:163858
|
|
abnormal primitive streak elongation |
J:163858
|
|
decreased embryo size |
J:163858
|
|
normal
embryo phenotype |
J:163858
|
|
embryonic lethality, incomplete penetrance |
J:163858
|
|
incomplete rostral neuropore closure |
J:163858
|
Trpm7tm1Clph/Trpm7tm1.1Clph
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S4/SvJae * C57BL/6 * CBA
|
embryonic lethality, complete penetrance |
J:140630
|
Ubr4tm1.2Nkt/Ubr4tm1.2Nkt
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S6/SvEvTac * C57BL/6 * CBA * SJL
|
abnormal atrioventricular cushion morphology |
J:203460
|
|
abnormal brain morphology |
J:203460
|
|
abnormal cell death |
J:203460
|
|
abnormal fourth ventricle morphology |
J:203460
|
|
abnormal head morphology |
J:203460
|
|
abnormal heart development |
J:203460
|
|
abnormal interventricular septum morphology |
J:203460
|
|
abnormal lateral ganglionic eminence morphology |
J:203460
|
|
abnormal liver parenchyma morphology |
J:203460
|
|
abnormal liver vasculature morphology |
J:203460
|
|
abnormal medial ganglionic eminence morphology |
J:203460
|
|
decreased brain size |
J:203460
|
|
dilated liver sinusoidal space |
J:203460
|
|
normal
embryo phenotype |
J:203460
|
|
embryonic growth retardation |
J:203460
|
|
increased cell proliferation |
J:203460
|
|
lethality throughout fetal growth and development, complete penetrance |
J:203460
|
|
liver hypoplasia |
J:203460
|
|
thin ventricular wall |
J:203460
|
Vps52tm1.1Kab/Vps52tm1.2Kab
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: C57BL * C57BL/6 * CBA * DBA
|
abnormal embryonic tissue morphology |
J:190873
|
|
abnormal vitelline vasculature morphology |
J:190873
|
|
disorganized yolk sac vascular plexus |
J:190873
|
|
embryonic lethality |
J:190873
|
Wnt7btm2Amc/Wnt7btm2.1Amc
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129X1/SvJ * C57BL/6 * CBA
|
abnormal kidney cell proliferation |
J:142685
|
|
abnormal kidney collecting duct epithelium morphology |
J:142685
|
|
abnormal kidney medulla development |
J:142685
|
|
abnormal kidney morphology |
J:142685
|
|
abnormal lung development |
J:134483
|
|
abnormal right lung middle lobe morphology |
J:134483
|
|
abnormal tracheal cartilage morphology |
J:134483
|
|
absent kidney medulla |
J:142685
|
|
atelectasis |
J:134483
|
|
cyanosis |
J:134483
|
|
decreased kidney cell proliferation |
J:142685
|
|
decreased lung weight |
J:134483
|
|
decreased mesenchymal cell proliferation involved in lung development |
J:134483
|
|
hydroureter |
J:142685
|
|
increased kidney apoptosis |
J:142685
|
|
lung hemorrhage |
J:134483
|
|
neonatal lethality, complete penetrance |
J:134483
|
|
small lung |
J:134483
|
|
thin lung-associated mesenchyme |
J:134483
|
|
truncated loop of Henle |
J:142685
|
Zfp568Gt(P103E09)Wrst/Zfp568Gt(RRU161)Byg
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * CBA
|
abnormal embryo development |
J:168015
|
Zic3tm1.1Smwa/Y
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: C57BL/6 * CBA
|
abnormal gastrulation |
J:194989
|
|
abnormal heart looping |
J:194989
|
|
abnormal heart morphology |
J:194989
|
|
abnormal neural tube morphology |
J:194989
|
Zic3tm2.1Jwb/Y
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6 * CBA
|
abnormal anus morphology |
J:192577
|
|
abnormal axial skeleton morphology |
J:192577
|
|
abnormal direction of heart looping |
J:192577
|
|
abnormal embryo development |
J:192577
|
|
abnormal eye morphology |
J:192577
|
|
abnormal heart looping |
J:192577
|
|
abnormal heart position or orientation |
J:192577
|
|
abnormal inferior vena cava morphology |
J:192577
|
|
abnormal lung position or orientation |
J:192577
|
|
abnormal neural tube morphology |
J:192577
|
|
abnormal stomach position or orientation |
J:192577
|
|
atrial septal defect |
J:192577
|
|
cleft palate |
J:192577
|
|
dextrocardia |
J:192577
|
|
embryonic growth retardation |
J:192577
|
|
exencephaly |
J:192577
|
|
heterotaxia |
J:192577
|
|
hindlimb paralysis |
J:192577
|
|
kinked tail |
J:192577
|
|
lethality throughout fetal growth and development, incomplete penetrance |
J:192577
|
|
right-sided stomach |
J:192577
|
|
ventricular septal defect |
J:192577
|
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