Slc22a5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Slc22a5
solute carrier family 22 (organic cation transporter), member 5
MGI:1329012

19 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Slc22a5^em1(IMPC)Bay/Slc22a5^em1(IMPC)Bay C57BL/6N-Slc22a5^em1(IMPC)Bay/Bay	embryonic lethality prior to organogenesis	J:211773
	preweaning lethality, complete penetrance	J:211773
Slc22a5^jvs/Slc22a5^jvs C3.OH-H2^o2 Slc22a5^jvs	abnormal corpus epididymis morphology	J:53598
	abnormal epididymis morphology	J:53598
	abnormal glucose homeostasis	J:31000
	abnormal hepatocyte morphology	J:31026
	abnormal male reproductive system morphology	J:53598
	abnormal renal reabsorption	J:18523
	aminoaciduria	J:18523
	cardiac hypertrophy	J:13736, J:40286
	decreased circulating carnitine level	J:18523
	hepatic steatosis	J:31000
	hypoglycemia	J:31000
	increased circulating ammonia level	J:31000
	increased epididymis weight	J:53598
	pale liver	J:14288
	postnatal growth retardation	J:40286
	premature death	J:40286
	normal reproductive system phenotype	J:14288

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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