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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Trex1
three prime repair exonuclease 1
MGI:1328317
17 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Arih1em3Gpt/Arih1em3Gpt
Lyz2em1(icre)Gpt/Lyz2+
Trex1em1Gpt/Trex1em1Gpt
C57BL/6JGpt-Arih1em3Gpt Trex1em1Gpt Lyz2em1(icre)Gpt 		normal growth/size/body region phenotype J:330879
normal immune system phenotype J:330879
normal mortality/aging J:330879
Cgastm1a(EUCOMM)Hmgu/Cgastm1a(EUCOMM)Hmgu
Trex1tm1Tld/Trex1tm1Tld
involves: 129P2/OlaHsd * C57BL/6N 		increased susceptibility to Retroviridae infection J:234263
Del(1Aim2-Ifi205)1Stsn/+
Trex1tm1Tld/Trex1tm1Tld
involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6N 		heart inflammation J:234263
increased autoantibody level J:234263
increased inflammatory response J:234263
kidney inflammation J:234263
myositis J:234263
premature death J:234263
stomach inflammation J:234263
Del(1Aim2-Ifi205)1Stsn/Del(1Aim2-Ifi205)1Stsn
Trex1tm1Tld/Trex1tm1Tld
involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6N 		heart inflammation J:234263
increased autoantibody level J:234263
increased inflammatory response J:234263
kidney inflammation J:234263
myositis J:234263
premature death J:234263
stomach inflammation J:234263
Ighmtm1Cgn/Ighmtm1Cgn
Trex1tm1Tld/Trex1tm1Tld
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 		cardiac fibrosis J:181257
increased inflammatory response J:181257
kidney inflammation J:181257
myocarditis J:181257
premature death J:181257
normal renal/urinary system phenotype J:181257
tubular nephritis J:181257
Mavstm1Itl/Mavstm1Itl
Trex1tm1Tld/Trex1tm1Tld
involves: 129P2/OlaHsd * C57BL/6 		increased inflammatory response J:181257
myocarditis J:181257
myositis J:181257
premature death J:181257
skin inflammation J:181257
stomach inflammation J:181257
Rag2tm1.1Cgn/Rag2tm1.1Cgn
Trex1tm1Tld/Trex1tm1Tld
involves: 129P2/OlaHsd * C57BL/6 		normal immune system phenotype J:181257
normal mortality/aging J:181257
Sting1tm1Gnb/Sting1tm1Gnb
Trex1tm1Tld/Trex1tm1Tld
involves: 129P2/OlaHsd * C57BL/6 		normal immune system phenotype J:181257
normal mortality/aging J:181257
Tcratm1Mom/Tcratm1Mom
Trex1tm1Tld/Trex1tm1Tld
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 		colitis J:181257
normal immune system phenotype J:181257
increased inflammatory response J:181257
normal mortality/aging J:181257
myositis J:181257
skin inflammation J:181257
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory