Ahnak Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ahnak
AHNAK nucleoprotein
MGI:1316648

15 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ahnak^{tm1b(KOMP)Mbp}/Ahnak⁺ C57BL/6N-Ahnak^{tm1b(KOMP)Mbp}/H	improved glucose tolerance	J:211773
	increased large unstained cell number	J:211773
	increased monocyte cell number	J:211773
Ahnak^{tm1b(KOMP)Mbp}/Ahnak^{tm1b(KOMP)Mbp} C57BL/6N-Ahnak^{tm1b(KOMP)Mbp}/H	preweaning lethality, incomplete penetrance	J:211773
Ahnak^tm1Tak/Ahnak^tm1Tak involves: 129S1/Sv * 129X1/SvJ	no abnormal phenotype detected	J:92500
Ahnak^tm1Vtm/Ahnak^tm1Vtm involves: 129S1/Sv * C57BL/6	abnormal T cell activation	J:131148
	abnormal T-helper 1 physiology	J:131148
	decreased interferon-gamma secretion	J:131148
	decreased interleukin-2 secretion	J:131148
	decreased T cell proliferation	J:131148
	increased interleukin-4 secretion	J:131148
	increased susceptibility to parasitic infection	J:131148
Ahnak^tm1Ysb/Ahnak^tm1Ysb involves: 129S4/SvJae	decreased body weight	J:167048
	decreased susceptibility to diet-induced obesity	J:167048
	decreased total body fat amount	J:167048

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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