Dhrs3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dhrs3
dehydrogenase/reductase 3
MGI:1315215

28 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dhrs3^{tm1(NCOM)Mfgc}/Dhrs3^{tm1(NCOM)Mfgc} involves: C57BL/6 * C57BL/6N	abnormal enzyme/coenzyme activity	J:214109
	abnormal retinol level	J:214109
	abnormal retinol metabolism	J:214109
	cleft palate	J:214109
	edema	J:214109
	eyelids open at birth	J:214109
	microphthalmia	J:214109
	perinatal lethality, complete penetrance	J:214109
Dhrs3^tm1Lex/Dhrs3⁺ involves: 129S5/SvEvBrd * C57BL/6J	enhanced sensorimotor gating	J:171883
Dhrs3^tm1Lex/Dhrs3^tm1Lex involves: 129S5/SvEvBrd * C57BL/6	abnormal axial skeleton morphology	J:203823
	abnormal craniofacial morphology	J:203823
	abnormal heart morphology	J:203823
	abnormal interventricular septum morphology	J:203823
	abnormal retinol metabolism	J:203823
	absent gastric milk in neonates	J:203823
	atrial septal defect	J:203823
	cervical vertebral fusion	J:203823
	decreased birth body size	J:203823
	delayed bone ossification	J:203823
	double outlet right ventricle	J:203823
	eyelids open at birth	J:203823
	failure of palatal shelf elevation	J:203823
	fetal growth retardation	J:203823
	micrognathia	J:203823
	neonatal lethality, complete penetrance	J:203823
	perinatal lethality, incomplete penetrance	J:203823
	ventricular septal defect	J:203823
	vertebral fusion	J:203823
Dhrs3^tm1Lex/Dhrs3^tm1Lex involves: 129S5/SvEvBrd * C57BL/6J	preweaning lethality, complete penetrance	J:171883
Dhrs3^tm1Lex/Dhrs3^tm1Lex Tg(RARE-Hspa1b/lacZ)12Jrt/0 involves: 129S5/SvEvBrd * C57BL/6 * CD-1	abnormal embryo development	J:203823

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/09/2024 MGI 6.23