Slit3 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Slit3
slit guidance ligand 3
MGI:1315202

6 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Ndst1^tm1Je/Ndst1^tm1Je Slit3^tm1.1Dor/Slit3⁺ Tg(Tek-cre)1Ywa/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	diaphragmatic hernia	J:208012
Ndst1^tm1Je/Ndst1^tm1Je Slit3^tm1.1Dor/Slit3^tm1.1Dor Tg(Tek-cre)1Ywa/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	diaphragmatic hernia	J:208012
Slit1^tm1.1Matl/Slit1^tm1.1Matl Slit2^tm1Matl/Slit2^tm1Matl Slit3^tm1.1Dor/Slit3⁺ involves: 129S1/Sv * 129S2/SvPas	abnormal axon guidance	J:89780
	abnormal spinal cord lateral column morphology	J:89780
	abnormal spinal cord ventral commissure morphology	J:89780
Slit1^tm1.1Matl/Slit1^tm1.1Matl Slit2^tm1Matl/Slit2^tm1Matl Slit3^tm1.1Dor/Slit3^tm1.1Dor involves: 129S1/Sv * 129S2/SvPas	abnormal axon guidance	J:89780
	abnormal spinal cord lateral column morphology	J:89780
Slit2^tm1Matl/Slit2^tm1Matl Slit3^tm1.1Dor/Slit3^tm1.1Dor involves: 129S1/Sv * 129S2/SvPas	abnormal mammary gland duct morphology	J:141875
	increased mammary gland epithelial cell proliferation	J:141875

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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