Marco Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Marco
macrophage receptor with collagenous structure
MGI:1309998

12 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Marco^tm1Ktry/Marco^tm1Ktry B6.129S6-Marco^tm1Ktry	abnormal macrophage physiology	J:115081
	abnormal spleen marginal zone morphology	J:122271
	impaired macrophage phagocytosis	J:115081
	increased inflammatory response	J:115081
	increased susceptibility to bacterial infection	J:115081, J:122271
	increased susceptibility to induced morbidity/mortality	J:115081
Marco^tm1Spt/Marco^tm1Spt C57BL/6-Marco^tm1Spt	abnormal dendritic cell chemotaxis	J:204315
	abnormal dendritic cell physiology	J:204315
	increased interferon-gamma secretion	J:204315
Marco^{tm2b(EUCOMM)Hmgu}/Marco^{tm2b(EUCOMM)Hmgu} C57BL/6N-Marco^{tm2b(EUCOMM)Hmgu}/Ieg	abnormal gait	J:211773
	hyperactivity	J:211773
	increased circulating alkaline phosphatase level	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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