Cdc7 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cdc7
cell division cycle 7
MGI:1309511

25 phenotypes from 3 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cdc7^{tm1.1(KOMP)Vlcg}/Cdc7⁺ C57BL/6N-Cdc7^{tm1.1(KOMP)Vlcg}/Tcp	abnormal skin morphology	J:211773
	decreased neutrophil cell number	J:211773
	increased lymphocyte cell number	J:211773
Cdc7^{tm1.1(KOMP)Vlcg}/Cdc7^{tm1.1(KOMP)Vlcg} C57BL/6N-Cdc7^{tm1.1(KOMP)Vlcg}/Tcp	embryonic lethality prior to organogenesis	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Cdc7^tm1Hmas/Cdc7^tm1Hmas involves: 129S/Sv * C57BL/6	embryonic lethality between implantation and somite formation, complete penetrance	J:76497
Cdc7^tm1Hmas/Cdc7^tm1Hmas involves: 129S/Sv * C57BL/6	inner cell mass degeneration	J:76497
Cdc7^tm1Hmas/Cdc7^tm1Hmas Tg(EF1A-Cdc7)DKO28Hmas/0 involves: 129S/Sv * C57BL/6	abnormal cell cycle	J:85942
	abnormal female reproductive system morphology	J:85942
	abnormal gametogenesis	J:85942
	abnormal male reproductive system morphology	J:85942
	abnormal seminiferous tubule morphology	J:85942
	absent ovarian follicles	J:85942
	arrest of male meiosis	J:85942
	curly tail	J:85942
	decreased body size	J:85942
	decreased DNA replication	J:85942
	normal immune system phenotype	J:85942
	multinucleated giant male germ cells	J:85942
	postnatal lethality, incomplete penetrance	J:85942
	prenatal lethality, incomplete penetrance	J:85942
	small ovary	J:85942
	small testis	J:85942
Cdc7^tm1Hmas/Cdc7^tm1Hmas Tg(EF1A-Cdc7)DKO28Hmas/Tg(EF1A-Cdc7)DKO28Hmas involves: 129S/Sv * C57BL/6	no abnormal phenotype detected	J:85942

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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