Egr3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Egr3
early growth response 3
MGI:1306780

22 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Egr3^tm1.1Kfuji/Egr3^tm1.1Kfuji Tg(Cd4-cre)1Cwi/0 involves: C57BL/6 * DBA/2	decreased transforming growth factor beta level	J:205814
Egr3^tm1Jmi/Egr3^tm1Jmi involves: C57BL/6	abnormal gait	J:243559
	abnormal sympathetic neuron morphology	J:196371
	scoliosis	J:243559
Egr3^tm1Jmi/Egr3^tm1Jmi Not Specified	abnormal cholinergic neuron morphology	J:160727
	abnormal dorsal root ganglion morphology	J:49575
	abnormal excitatory postsynaptic potential	J:76256
	abnormal gait	J:49575
	abnormal limb posture	J:49575
	abnormal muscle spindle morphology	J:76256
	abnormal nervous system physiology	J:76256
	abnormal proprioceptive neuron morphology	J:49575, J:76256
	abnormal somatic nervous system physiology	J:76256
	abnormal somatic sensory system morphology	J:49575
	absent muscle spindles	J:49575
	ataxia	J:49575
	blepharoptosis	J:49575
	decreased motor neuron number	J:160727
	postnatal lethality, incomplete penetrance	J:49575
	scoliosis	J:49575
	tremors	J:49575
Egr3^tm1Jmi/Egr3^tm2.1Wgt Tg(DBH-cre,-taulacZ)1Wgt/0 involves: 129P2/OlaHsd * C57BL/6 * SJL	abnormal sympathetic neuron innervation pattern	J:196371
	normal behavior/neurological phenotype	J:196371
	blepharoptosis	J:196371
	superior cervical ganglion degeneration	J:196371

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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