Lrp6Cd/Lrp6+
A-Lrp6Cd
|
abnormal caudal vertebrae morphology |
J:13045
|
abnormal lumbar vertebrae morphology |
J:13045
|
abnormal sacral vertebrae morphology |
J:13045
|
abnormal vertebrae morphology |
J:13045
|
kinked tail |
J:13045,
J:58433
|
small caudal vertebrae |
J:13045
|
vertebral fusion |
J:13045
|
Lrp6Cd/Lrp6+
involves: A * 129/Sv
|
kinked tail |
J:58433
|
Lrp6Cd/Lrp6+
involves: A * C57BL/6
|
kinked tail |
J:58433
|
Lrp6Cd/Lrp6+
involves: A * DBA
|
kinked tail |
J:58433
|
Lrp6Cd/Lrp6Cd
A-Lrp6Cd
|
abnormal caudal vertebrae morphology |
J:13045,
J:101423
|
abnormal coat appearance |
J:13045
|
abnormal cranium morphology |
J:13045
|
abnormal frontal bone morphology |
J:13045
|
abnormal head movements |
J:13045
|
abnormal head shape |
J:13045
|
abnormal lumbar vertebrae morphology |
J:13045,
J:101423
|
abnormal molar cusp morphology |
J:12999
|
abnormal nose morphology |
J:13045
|
abnormal outer ear morphology |
J:13045
|
abnormal sacral vertebrae morphology |
J:13045
|
abnormal somite development |
J:101423
|
abnormal tail ring morphology |
J:12999,
J:13045
|
abnormal tooth development |
J:12998
|
abnormal tooth eruption |
J:12999,
J:13045
|
abnormal vertebrae morphology |
J:13045
|
anophthalmia |
J:13045
|
caudal vertebral fusion |
J:13045,
J:101423
|
decreased birth body size |
J:12998
|
decreased body size |
J:13045,
J:58433
|
decreased molar number |
J:12998,
J:12999
|
decreased somite size |
J:101423
|
delayed bone ossification |
J:13045
|
delayed cranial suture closure |
J:13045
|
embryonic lethality before implantation, incomplete penetrance |
J:13045,
J:58433
|
exencephaly |
J:13045,
J:58433,
J:101423
|
growth retardation of molars |
J:12998
|
hemivertebra |
J:101423
|
kinked tail |
J:13045
|
long upper incisors |
J:13045
|
microphthalmia |
J:12999,
J:13045
|
neonatal lethality, incomplete penetrance |
J:13045,
J:58433
|
postnatal growth retardation |
J:13045
|
prenatal lethality, incomplete penetrance |
J:13045
|
short incisors |
J:12998
|
small caudal vertebrae |
J:13045
|
small cranium |
J:13045
|
small lower incisors |
J:12999
|
small molars |
J:12998,
J:12999
|
sparse hair |
J:12999,
J:13045
|
thin neurocranium |
J:13045
|
Lrp6Cd/Lrp6Gt(Ex187)Byg
involves: 129P2/OlaHsd * A
|
abnormal vertebrae development |
J:101423
|
exencephaly |
J:101423
|
kinked tail |
J:101423
|
prenatal lethality |
J:101423
|
vertebral fusion |
J:101423
|
Lrp6Gt(Ex187)Byg/Lrp6+
involves: 129/Sv * 129P2/OlaHsd * C57BL/6J * FVB/N
|
decreased bone mineral density |
J:111359
|
Lrp6Gt(Ex187)Byg/Lrp6Gt(Ex187)Byg
involves: 129P2/OlaHsd
|
abnormal external female genitalia morphology |
J:155250
|
abnormal external male genitalia morphology |
J:155250
|
incomplete somite formation |
J:93008
|
Lrp6Gt(Ex187)Byg/Lrp6Gt(Ex187)Byg
involves: 129P2/OlaHsd * C57BL/6
|
abnormal cerebellum morphology |
J:64989
|
abnormal digit morphology |
J:64989
|
abnormal midbrain morphology |
J:64989
|
abnormal midbrain-hindbrain boundary morphology |
J:64989
|
abnormal tail bud morphology |
J:64989
|
absent apical ectodermal ridge |
J:64989
|
absent inferior colliculus |
J:64989
|
absent paraxial mesoderm |
J:64989
|
absent vertebrae |
J:64989
|
exencephaly |
J:64989
|
forelimb oligodactyly |
J:64989
|
incomplete somite formation |
J:64989
|
perinatal lethality, complete penetrance |
J:64989
|
sirenomelia |
J:64989
|
small tail bud |
J:64989
|
spina bifida |
J:64989
|
Lrp6Gt(LST067)Byg/Lrp6+
B6.Cg-Lrp6Gt(LST067)Byg
|
abnormal brown adipose tissue morphology |
J:182772
|
abnormal liver morphology |
J:182772
|
abnormal liver physiology |
J:182772
|
decreased body weight |
J:182772
|
decreased circulating glucose level |
J:182772
|
decreased liver triglyceride level |
J:182772
|
decreased susceptibility to diet-induced obesity |
J:182772
|
decreased susceptibility to induced hypothermia |
J:182772
|
improved glucose tolerance |
J:182772
|
increased brown fat cell number |
J:182772
|
increased circulating adiponectin level |
J:182772
|
increased insulin sensitivity |
J:182772
|
Lrp6Gt(LST067)Byg/Lrp6+
involves: 129P2/OlaHsd
|
abnormal lipid homeostasis |
J:155275
|
Lrp6Gw/Lrp6+
involves: 101/H * BALB/c * C3H/HeH
|
abnormal forebrain morphology |
J:170646
|
abnormal head morphology |
J:170646
|
kinked tail |
J:170646
|
Lrp6Gw/Lrp6+
involves: 101/H * BALB/cOlaHsd * C3H/HeH
|
kinked tail |
J:93195
|
Lrp6Gw/Lrp6Gw
involves: 101/H * BALB/c * C3H/HeH
|
abnormal head morphology |
J:170646
|
abnormal telencephalon morphology |
J:170646
|
forebrain hypoplasia |
J:170646
|
kinked tail |
J:170646
|
Lrp6Gw/Lrp6Gw
involves: 101/H * BALB/cOlaHsd * C3H/HeH
|
abnormal forebrain development |
J:93195
|
decreased embryo size |
J:93195
|
exencephaly |
J:93195
|
Lrp6m10Bei/Lrp6m10Bei
involves: A/J * C57BL/6
|
abnormal neural tube closure |
J:199782
|
craniorachischisis |
J:199782
|
exencephaly |
J:199782
|
spina bifida |
J:199782
|
Lrp6rs/Lrp6Gt(Ex187)Byg
involves: 129P2/OlaHsd * BALB/c
|
incomplete somite formation |
J:93008
|
Lrp6rs/Lrp6rs
involves: BALB/c
|
abnormal dorsal-ventral polarity of the somites |
J:93008
|
abnormal paraxial mesoderm morphology |
J:93008
|
abnormal vertebrae morphology |
J:93008
|
abnormal vertebral arch morphology |
J:93008
|
curly tail |
J:93008
|
delayed bone ossification |
J:93008
|
fused dorsal root ganglion |
J:93008
|
incomplete somite formation |
J:93008
|
oligodactyly |
J:93008
|
osteoporosis |
J:93008
|
postnatal lethality, incomplete penetrance |
J:93008
|
rib fusion |
J:93008
|
short tail |
J:93008
|
spina bifida cystica |
J:93008
|
spina bifida occulta |
J:93008
|
Lrp6rs/Lrp6rs
involves: BALB/c * C57BL/6
|
curly tail |
J:93008
|
short tail |
J:93008
|
Lrp6skax26/Lrp6+
involves: 129S6/SvEvTac * C57BL/6J
|
curly tail |
J:206979
|
kinked tail |
J:206979
|
Lrp6skax26/Lrp6skax26
involves: 129S6/SvEvTac * C57BL/6J
|
abnormal orientation of outer hair cell stereociliary bundles |
J:206979
|
curly tail |
J:206979
|
kinked tail |
J:206979
|
Lrp6skax26/Lrp6skax26
involves: C57BL/6J
|
curly tail |
J:89098
|
kinked tail |
J:89098
|
Lrp6tm1.1Vari/Lrp6tm1.1Vari
involves: 129S1/Sv
|
no abnormal phenotype detected |
J:178499
|
Lrp6tm1.1Vari/Lrp6tm1.1Vari Twist2tm1(cre)Dor/Twist2+
involves: 129S1/Sv * 129X1/SvJ
|
delayed bone ossification |
J:178499
|
normal
skeleton phenotype |
J:178499
|
Lrp6tm1.1Vari/Lrp6tm1.2Vari Twist2tm1(cre)Dor/Twist2+
involves: 129S1/Sv * 129X1/SvJ
|
delayed bone ossification |
J:178499
|
normal
skeleton phenotype |
J:178499
|
Lrp6tm1.2Cjz/Lrp6Gt(Ex187)Byg
involves: 129P2/OlaHsd * C57BL/6J * CD-1 * SJL
|
abnormal external female genitalia morphology |
J:155250
|
abnormal external male genitalia morphology |
J:155250
|
abnormal eye development |
J:155250
|
abnormal limb morphology |
J:155250
|
exencephaly |
J:155250
|
failure of eyelid fusion |
J:155250
|
microphthalmia |
J:155250
|
retina coloboma |
J:155250
|
short tail |
J:155250
|
spina bifida |
J:155250
|
Lrp6tm1.2Cjz/Lrp6tm1.2Cjz
involves: C57BL/6J * CD-1 * SJL
|
abnormal digit morphology |
J:155250
|
abnormal external female genitalia morphology |
J:155250
|
abnormal external male genitalia morphology |
J:155250
|
abnormal eye development |
J:155250
|
abnormal forelimb morphology |
J:155250
|
abnormal hindlimb morphology |
J:155250
|
abnormal limb morphology |
J:155250
|
cleft palate |
J:155250
|
cleft upper lip |
J:155250
|
exencephaly |
J:155250
|
failure of eyelid fusion |
J:155250
|
forelimb oligodactyly |
J:155250
|
microphthalmia |
J:155250
|
polydactyly |
J:155250
|
protruding tongue |
J:155250
|
retina coloboma |
J:155250
|
short limbs |
J:155250
|
short tail |
J:155250
|
sirenomelia |
J:155250
|
spina bifida |
J:155250
|
Lrp6tm1.2Vari/Lrp6tm1.2Vari
involves: 129S1/Sv
|
neonatal lethality, complete penetrance |
J:178499
|
Lrp6tm1Arma/Lrp6+
C57BL/6-Lrp6tm1Arma
|
increased cholesterol level |
J:210538
|
increased circulating LDL cholesterol level |
J:210538
|
increased circulating triglyceride level |
J:210538
|
Lrp6tm1Arma/Lrp6tm1Arma
C57BL/6-Lrp6tm1Arma
|
abnormal fatty acids level |
J:210538
|
abnormal lipid homeostasis |
J:210538
|
abnormal liver morphology |
J:225450
|
enlarged liver |
J:210538
|
hepatic steatosis |
J:210538,
J:225450
|
hyperlipidemia |
J:210538
|
increased cholesterol level |
J:210538
|
increased circulating aspartate transaminase level |
J:210538
|
increased circulating bilirubin level |
J:210538
|
increased circulating LDL cholesterol level |
J:210538
|
increased circulating triglyceride level |
J:210538
|
increased circulating VLDL triglyceride level |
J:210538
|
increased liver cholesterol level |
J:210538,
J:225450
|
increased liver triglyceride level |
J:210538
|
insulin resistance |
J:210538
|
liver fibrosis |
J:225450
|
liver inflammation |
J:225450
|