Ptp4a2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ptp4a2
protein tyrosine phosphatase 4a2
MGI:1277117

46 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ptp4a2^em1(IMPC)Tcp/Ptp4a2^em1(IMPC)Tcp C57BL/6N-Ptp4a2^em1(IMPC)Tcp/Tcp	abnormal bone structure	J:211773
	abnormal skin morphology	J:211773
	abnormal stomach morphology	J:211773
	decreased body length	J:211773
	decreased lean body mass	J:211773
	decreased mean corpuscular volume	J:211773
	decreased prepulse inhibition	J:211773
	enlarged lymph nodes	J:211773
	increased grip strength	J:211773
	increased mean platelet volume	J:211773
	increased total body fat amount	J:211773
	short tibia	J:211773
	shortened QRS complex duration	J:211773
	small testis	J:211773
	thick skin	J:211773
Ptp4a2^{Gt(AQ0673)Wtsi}/Ptp4a2^{Gt(AQ0673)Wtsi} involves: 129P2/OlaHsd * C57BL/6	abnormal cauda epididymis morphology	J:209512, J:250112
	abnormal male germ cell physiology	J:209512
	abnormal maternal decidual layer morphology	J:190411
	abnormal seminiferous tubule epithelium morphology	J:209512
	abnormal seminiferous tubule morphology	J:209512, J:250112
	abnormal spermatogenesis	J:209512
	decreased birth body size	J:190411
	decreased birth weight	J:190411
	decreased body size	J:209512
	decreased body weight	J:190411
	decreased cell proliferation	J:190411
	decreased fetal weight	J:190411
	decreased litter size	J:209512
	decreased male germ cell number	J:209512, J:250112
	decreased placenta weight	J:190411
	decreased placental labyrinth size	J:190411
	decreased spleen weight	J:190411
	decreased spongiotrophoblast size	J:190411
	decreased testis weight	J:190411, J:209512, J:250112
	decreased trophoblast glycogen cell number	J:190411
	normal homeostasis/metabolism phenotype	J:209512
	increased male germ cell apoptosis	J:209512, J:250112
	male infertility	J:209512
	oligozoospermia	J:209512, J:250112
	postnatal growth retardation	J:190411
	preweaning lethality, incomplete penetrance	J:250112
	reduced male fertility	J:209512
	normal reproductive system phenotype	J:209512, J:250112
	slow postnatal weight gain	J:250112
	small seminiferous tubules	J:209512, J:250112
	small testis	J:209512, J:250112
	testicular atrophy	J:209512

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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