Pde8a Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pde8a
phosphodiesterase 8A
MGI:1277116

6 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pde8a^{tm1b(EUCOMM)Hmgu}/Pde8a^{tm1b(EUCOMM)Hmgu} C57BL/6N-Pde8a^{tm1b(EUCOMM)Hmgu}/H	decreased lean body mass	J:211773
	increased total body fat amount	J:211773
Pde8a^tm1Dgen/Pde8a^tm1Dgen B6.129P2-Pde8a^tm1Dgen	abnormal enzyme/coenzyme activity	J:118251
Pde8a^tm1Dgen/Pde8a^tm1Dgen B6.129P2-Pde8a^tm1Dgen	abnormal testosterone level	J:118251
Pde8a^tm1Dgen/Pde8a^tm1Dgen involves: 129P2/OlaHsd * C57BL/6J	decreased thermal nociceptive threshold	J:82809
	increased susceptibility to pharmacologically induced seizures	J:82809

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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