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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Robo1
roundabout guidance receptor 1
MGI:1274781
22 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Robo1tm1Matl/Robo1tm1Matl
Robo2tm1Mrt/Robo2tm1Mrt
involves: 129P2/OlaHsd 		abnormal axon guidance J:119469
abnormal diaphragm morphology J:193400
abnormal dorsal aorta morphology J:193400
abnormal foregut morphology J:193400
abnormal olfactory tract morphology J:119469
abnormal spinal cord ventral commissure morphology J:194150
abnormal stomach position or orientation J:193400
absent gastric milk in neonates J:193400
cyanosis J:193400
decreased cell migration J:193400
esophagus hypoplasia J:193400
neonatal lethality, complete penetrance J:193400
respiratory failure J:193400
short trachea J:193400
small esophagus J:193400
Robo1tm1Matl/Robo1tm1Matl
Robo2tm1Mrt/Robo2tm1Mrt
involves: 129P2/OlaHsd * C57BL/6 * CD-1 		abnormal anterior commissure morphology J:120131
abnormal axon guidance J:120131
abnormal dorsal telencephalic commissure morphology J:120131
abnormal innervation J:120131
decreased corpus callosum size J:120131
Robo1tm1Matl/Robo1tm1Matl
Robo2tm1Rilm/Robo2tm1Rilm
Shhtm1(EGFP/cre)Cjt/Shh+
involves: 129 		no abnormal phenotype detected J:193400
Robo1tm1Matl/Robo1tm1Matl
Robo2tm1Rilm/Robo2tm1Rilm
Tbx4tm1(cre)Tmj/Tbx4+
involves: 129 		no abnormal phenotype detected J:193400
Robo1tm1Matl/Robo1tm1Matl
Robo2tm1Rilm/Robo2tm1Rilm
Twist2tm1(cre)Dor/Twist2+
involves: 129 * 129X1/SvJ 		abnormal foregut morphology J:193400
diaphragmatic hernia J:193400
neonatal lethality J:193400
respiratory failure J:193400
small esophagus J:193400
Robo1tm1Matl/Robo1tm1Matl
Robo3tm1Matl/Robo3tm1Matl
involves: 129/Sv * CD-1 		abnormal axon guidance J:89438
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory