About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Bap1
Brca1 associated protein 1
MGI:1206586
51 phenotypes from 6 alleles in 4 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Bap1em1Test/Bap1+
involves: FVB
abnormal DNA methylation J:213725
abnormal epigenetic regulation of gene expression J:213725
normal hematopoietic system phenotype J:213725
increased colon tumor incidence J:231692
increased granulosa cell tumor incidence J:231692
increased incidence of tumors by chemical induction J:213725
increased lung carcinoma incidence J:231692
increased mammary adenocarcinoma incidence J:231692
increased mesothelioma incidence J:231692
increased ovary tumor incidence J:231692
increased skin tumor incidence J:231692
increased squamous cell carcinoma incidence J:213725
Bap1em1Test/Bap1em1Test
involves: FVB
embryonic lethality between implantation and placentation, complete penetrance J:213725
Bap1em2Test/Bap1+
involves: FVB
increased granulosa cell tumor incidence J:231692
increased incidence of tumors by chemical induction J:231692
increased lung carcinoma incidence J:231692
increased mammary adenocarcinoma incidence J:231692
increased mesothelioma incidence J:231692
increased ovary tumor incidence J:231692
increased pancreatic islet cell carcinoma incidence J:231692
increased skin tumor incidence J:231692
Bap1em3Test/Bap1+
involves: FVB
increased granulosa cell tumor incidence J:231692
increased incidence of tumors by chemical induction J:231692
increased lung carcinoma incidence J:231692
increased lymphoma incidence J:231692
increased mammary adenocarcinoma incidence J:231692
increased ovary tumor incidence J:231692
increased skin tumor incidence J:231692
Bap1tm1.1Geno/Bap1+
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
involves: C57BL/6 * C57BL/6NTac
abnormal hematopoietic system morphology/development J:187380
Bap1tm1.1Geno/Bap1tm1.1Geno
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
involves: C57BL/6 * C57BL/6NTac
abnormal bone marrow cell physiology J:187380
abnormal cardiac thrombosis J:187380
abnormal erythrocyte morphology J:187380
abnormal erythropoiesis J:187380
abnormal granulocyte morphology J:187380
abnormal hematopoietic stem cell physiology J:187380
abnormal myelopoiesis J:187380
abnormal neutrophil morphology J:187380
anemia J:187380
anisopoikilocytosis J:187380
cardiac muscle necrosis J:187380
enlarged spleen J:187380
extramedullary hematopoiesis J:187380
giant platelets J:187380
heart inflammation J:187380
increased hematopoietic stem cell number J:187380
increased leukemia incidence J:187380
increased leukocyte cell number J:187380
increased monocyte cell number J:187380
increased neutrophil cell number J:187380
increased nucleated erythrocyte cell number J:187380
myeloid hyperplasia J:187380
thrombocytopenia J:187380
Bap1tm1.2Geno/Bap1tm1.2Geno
involves: C57BL/6
embryonic growth retardation J:187380
embryonic lethality during organogenesis, complete penetrance J:187380
Bap1tm1a(EUCOMM)Hmgu/Bap1+
C57BL/6N-Bap1tm1a(EUCOMM)Hmgu/Wtsi
increased circulating alkaline phosphatase level J:211773
increased effector memory CD4-positive, alpha-beta T cell number J:211773
increased Ly6C low monocyte number J:211773
increased monocyte cell number J:211773
Bap1tm1a(EUCOMM)Hmgu/Bap1tm1a(EUCOMM)Hmgu
C57BL/6N-Bap1tm1a(EUCOMM)Hmgu/Wtsi
abnormal chorion morphology J:261316
abnormal placenta morphology J:261316
abnormal trophoblast layer morphology J:261316
abnormal visceral yolk sac morphology J:261316
embryonic lethality during organogenesis, incomplete penetrance J:261316
lethality throughout fetal growth and development, complete penetrance J:261316
preweaning lethality, complete penetrance J:211773

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/10/2019
MGI 6.14
The Jackson Laboratory