32 phenotypes from 6 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Birc5tm1Emc/Birc5+ involves: 129S1/Sv * 129X1/SvJ * Swiss	abnormal apoptosis	J:78103
	abnormal oxidative phosphorylation	J:78103
	increased susceptibility to injury	J:78103
Birc5tm1Emc/Birc5tm1Emc involves: 129S1/Sv * 129X1/SvJ * Swiss	embryonic lethality before implantation, complete penetrance	J:78103
Birc5tm1Mak/Birc5tm1Mak involves: 129P2/OlaHsd	no abnormal phenotype detected	J:90892
Birc5tm1Mak/Birc5tm1Mak Tg(Lck-cre)I57Jxm/0 involves: 129P2/OlaHsd	abnormal cell cycle	J:90892
	abnormal T cell morphology	J:90892
	abnormal thymus corticomedullary boundary morphology	J:90892
	decreased double-negative T cell number	J:90892
	decreased thymocyte number	J:90892
	increased T cell apoptosis	J:90892
	small thymus	J:90892
Birc5tm1Vaux/Birc5tm1Vaux C57BL/6-Birc5tm1Vaux	abnormal cell cycle	J:86384
	abnormal cell nucleus count	J:86384
	abnormal cell nucleus morphology	J:86384
	abnormal embryonic tissue morphology	J:86384
	abnormal mitotic spindle morphology	J:86384
	absent blastocoele	J:86384
	absent trophoblast giant cells	J:86384
	binucleate	J:86384
	embryonic lethality between implantation and somite formation, complete penetrance	J:86384
	failure of blastocyst to hatch from the zona pellucida	J:86384
	inner cell mass degeneration	J:86384
Birc5tm1Wnt/Birc5tm1Emc Tg(Cd4-cre)1Cwi/0 involves: 129S/SvEv * C57BL/6 * DBA/2	abnormal T cell differentiation	J:87435
Birc5tm1Wnt/Birc5tm1Emc Tg(Lck-cre)1Cwi/0 involves: 129S/SvEv * C57BL/6 * DBA/2	decreased double-positive T cell number	J:87435
	decreased T cell number	J:87435
	increased double-negative T cell number	J:87435
	small lymph nodes	J:87435
	thymus hypoplasia	J:87435
Tg(Dct-Birc5)21Gros/0 involves: C57BL/6 * CBA	decreased cellular sensitivity to ultraviolet irradiation	J:122181
	normal neoplasm	J:122181
Tg(KRT14-Birc5)19Gros/0 involves: C3H * C57BL/6	abnormal keratinocyte physiology	J:81530
	decreased incidence of tumors by chemical induction	J:81530