Cd46 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cd46
CD46 antigen, complement regulatory protein
MGI:1203290

13 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cd46^tm1Atk/Cd46^tm1Atk B6.129-Cd46^tm1Atk	abnormal Bruch membrane morphology	J:234294
	abnormal choriocapillaris morphology	J:234294
	abnormal optic choroid morphology	J:234294
	abnormal retina morphology	J:213630, J:234294
	abnormal retina outer nuclear layer morphology	J:234294
	abnormal retina photoreceptor morphology	J:234294
	abnormal retina pigment epithelium morphology	J:234294
	increased susceptibility to age-related retinal degeneration	J:234294
	increased susceptibility to induced choroid neovascularization	J:213630
	normal reproductive system phenotype	J:213630
	retina photoreceptor degeneration	J:234294
Cd46^tm1Osb/Cd46^tm1Osb involves: 129S2/SvPas * C57BL/6	abnormal fertilization	J:82516
	increased litter size	J:82516
	normal reproductive system phenotype	J:82516

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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