Angpt2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Angpt2
angiopoietin 2
MGI:1202890

20 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Angpt1^tm1.1Seq/Angpt1^tm1.1Seq Angpt2^{tm1c(KOMP)Seq}/Angpt2^{tm1c(KOMP)Seq} Gt(ROSA)26Sor^{tm1(rtTA,EGFP)Nagy}/? Tg(tetO-cre)1Jaw/0 involves: 129 * C57BL/6NCr	abnormal anterior eye segment morphology	J:217296
	abnormal cornea morphology	J:217296
	abnormal eye morphology	J:217296
	abnormal eye physiology	J:217296
	abnormal intraocular pressure	J:217296
	abnormal lymphatic vessel morphology	J:217296
	abnormal retina layer morphology	J:217296
	abnormal retina nerve fiber layer morphology	J:217296
	absent Schlemm's canal	J:217296
	buphthalmos	J:217296
	corneal vascularization	J:217296
	decreased visual acuity	J:217296
	increased cornea size	J:217296
	increased eye anterior chamber depth	J:217296
	thin retina ganglion layer	J:217296
	thin retina inner nuclear layer	J:217296
	thin retina outer nuclear layer	J:217296
Angpt2^{tm2(Angpt1)Gdy}/Angpt2^{tm2(Angpt1)Gdy} involves: 129P2/OlaHsd * C57BL/6	abnormal angiogenesis	J:89618
	normal homeostasis/metabolism phenotype	J:89618
	normal immune system phenotype	J:89618

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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