Gtf2i Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gtf2i
general transcription factor II I
MGI:1202722

34 phenotypes from 7 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gtf2i^{Gt(RRI105)Byg}/Gtf2i^{Gt(RRI105)Byg} involves: 129P2/OlaHsd * C57BL/6	embryonic lethality, complete penetrance	J:143508
Gtf2i^Gt(XC455)Byg/Gtf2i^Gt(XC455)Byg involves: 129P2/OlaHsd * C57BL/6	embryonic lethality, complete penetrance	J:143508
Gtf2i^Gt(XE029)Byg/Gtf2i⁺ involves: 129P2/OlaHsd * C57BL/6	abnormal craniofacial morphology	J:143508
	decreased body size	J:143508
	exencephaly	J:143508
	narrow head	J:143508
Gtf2i^Gt(XE029)Byg/Gtf2i^Gt(XE029)Byg involves: 129P2/OlaHsd * C57BL/6	abnormal brain development	J:143508
	decreased embryo size	J:143508
	dilated allantois	J:143508
	distended pericardium	J:143508
	embryonic growth retardation	J:143508
	embryonic lethality, complete penetrance	J:143508
	exencephaly	J:143508
	failure of chorioallantoic fusion	J:143508
	failure of heart looping	J:143508
	internal hemorrhage	J:143508
	midline facial cleft	J:143508
	pharyngeal arch hypoplasia	J:143508
Gtf2i^{Gt(YTA365)Byg}/Gtf2i^{Gt(YTA365)Byg} involves: 129P2/OlaHsd * CD-1	embryonic lethality, complete penetrance	J:196809
Gtf2i^tm1.1Bdash/Gtf2i^tm1.1Bdash involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J	no abnormal phenotype detected	J:236328
Gtf2i^tm1.2Bdash/Gtf2i^tm1.2Bdash involves: 129S1/Sv * 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J	embryonic lethality during organogenesis, complete penetrance	J:236328
Gtf2i^tm1Vcam/Gtf2i⁺ involves: 129S1/Sv * 129X1/SvJ * CD-1	abnormal behavior	J:204278
	normal behavior/neurological phenotype	J:204278
	decreased exploration in new environment	J:204278
	decreased vertical activity	J:204278
	increased anxiety-related response	J:204278
Gtf2i^tm1Vcam/Gtf2i^tm1Vcam involves: 129S1/Sv * 129X1/SvJ * CD-1	abnormal craniofacial morphology	J:204278
	abnormal embryo development	J:204278
	absent embryonic epiblast	J:204278
	normal behavior/neurological phenotype	J:204278
	broad nasal bridge	J:204278
	decreased embryonic epiblast cell proliferation	J:204278
	embryonic lethality, incomplete penetrance	J:204278
	normal nervous system phenotype	J:204278
	prenatal lethality, incomplete penetrance	J:204278
	reduced female fertility	J:204278
	reduced male fertility	J:204278
	short snout	J:204278
	small testis	J:204278
	testicular atrophy	J:204278

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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