Chrna9 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Chrna9
cholinergic receptor, nicotinic, alpha polypeptide 9
MGI:1202403

12 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Chrna9^tm1Bedv/Chrna9^tm1Bedv either: CB.129S1-Chrna9^tm1Bedv or (involves: 129S1/Sv) or (involves: 129S1/Sv * CBA/CaJ)	abnormal cochlear IHC efferent innervation pattern	J:55406
	abnormal cochlear nerve compound action potential	J:55406, J:100073
	abnormal cochlear OHC efferent innervation pattern	J:55406
	abnormal distortion product otoacoustic emission	J:55406
	abnormal sensory neuron innervation pattern	J:55406
	normal hearing/vestibular/ear phenotype	J:55406, J:100073
Chrna9^tm1Bedv/Chrna9^tm1Bedv Not Specified	abnormal cochlear outer hair cell physiology	J:130585
Chrna9^tm1Elgo/Chrna9⁺ involves: 129S4/SvJae * FVB/N	abnormal cochlear inner hair cell physiology	J:144698
	abnormal distortion product otoacoustic emission	J:144698
	decreased susceptibility to noise-induced hearing loss	J:144698
	increased or absent threshold for auditory brainstem response	J:144698
Chrna9^tm1Elgo/Chrna9^tm1Elgo involves: 129S4/SvJae * FVB/N	abnormal cochlear inner hair cell physiology	J:144698
	abnormal cochlear outer hair cell physiology	J:144698
	abnormal distortion product otoacoustic emission	J:144698
	abnormal inhibitory postsynaptic currents	J:144698
	decreased susceptibility to noise-induced hearing loss	J:144698
	increased or absent threshold for auditory brainstem response	J:144698
Chrna9^{tm2a(EUCOMM)Wtsi}/Chrna9^{tm2a(EUCOMM)Wtsi} C57BL/6N-Chrna9^{tm2a(EUCOMM)Wtsi}/H	decreased body weight	J:165965

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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