Gnmt Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gnmt
glycine N-methyltransferase
MGI:1202304

20 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gnmt^tm1Cwa/Gnmt^tm1Cwa involves: 129 * C57BL/6J	abnormal amino acid level	J:110257
Gnmt^tm1Ymac/Gnmt⁺ involves: 129/Sv * C57BL/6	decreased liver weight	J:147857
Gnmt^tm1Ymac/Gnmt^tm1Ymac involves: 129 * C57BL/6	abnormal liver morphology	J:147857
	decreased circulating glucose level	J:147857
	decreased leukocyte cell number	J:147857
	decreased monocyte cell number	J:147857
	decreased neutrophil cell number	J:147857
	dilated liver sinusoidal space	J:147857
	enlarged liver	J:147857
	hepatic necrosis	J:147857
	hepatic steatosis	J:146081
	increased circulating alanine transaminase level	J:146081, J:147857
	increased circulating cholesterol level	J:147857
	increased circulating methionine level	J:147857
	increased hepatic hemangioma incidence	J:146081
	increased hepatocellular carcinoma incidence	J:146081
	increased liver glycogen level	J:147857
	increased liver weight	J:147857
	liver degeneration	J:147857
	liver vascular congestion	J:147857

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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