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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Eomes
eomesodermin
MGI:1201683
46 phenotypes from 11 alleles in 12 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Eomestm1.1(cre/ERT2)Sjar/Eomes+
involves: 129S/SvEv
no abnormal phenotype detected J:198846
Eomestm1.1(cre/ERT2)Sjar/Eomestm1.1(cre/ERT2)Sjar
involves: 129S/SvEv
embryonic lethality between implantation and placentation J:198846
Eomestm1.1Bflu/Eomestm1.1Bflu
Tg(Cd4-cre)1Cwi/0
involves: C57BL/6 * DBA/2 * SJL
abnormal leukocyte migration J:163822
decreased memory T cell number J:163822
increased tumor incidence J:163822
Eomestm1.1Rob/Eomestm1.1Rob
involves: 129S/SvEv * C57BL/6 * CBA
abnormal trophoblast layer morphology J:131055
embryonic lethality between implantation and somite formation, complete penetrance J:131055
Eomestm1.1Whk/Eomestm1.1Whk
Tg(Six3-cre)69Frty/0
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 * DBA/2
abnormal optic nerve morphology J:130570
abnormal retinal ganglion cell morphology J:130570
decreased retinal ganglion cell number J:130570
increased retinal apoptosis J:130570
thin retinal ganglion layer J:130570
Eomestm1Apr/Eomes+
involves: C57BL/6
decreased memory T cell number J:112679
decreased NK cell number J:112679
Eomestm1Apr/Eomestm1Apr
Not Specified
abnormal anterior primitive streak morphology J:60897
abnormal egg cylinder morphology J:60897
abnormal primitive streak elongation J:60897
abnormal trophoblast layer morphology J:60897
absent mesoderm J:60897
absent primitive node J:60897
embryonic growth arrest J:60897
embryonic lethality between implantation and somite formation, complete penetrance J:60897
Eomestm1b(EUCOMM)Wtsi/Eomes+
C57BL/6N-Eomestm1b(EUCOMM)Wtsi/H
decreased bone mineral content J:211773
decreased lean body mass J:211773
increased total body fat amount J:211773
Eomestm1b(EUCOMM)Wtsi/Eomestm1b(EUCOMM)Wtsi
C57BL/6N-Eomestm1b(EUCOMM)Wtsi/H
preweaning lethality, complete penetrance J:211773
Eomestm1Jrt/Eomestm1Jrt
either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * ICR)
absent trophectoderm J:98502
absent trophoblast giant cells J:98502
embryonic growth arrest J:98502
embryonic lethality before implantation, complete penetrance J:98502
failure of embryo implantation J:98502
Eomestm1Rob/Eomestm1.1Rob
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S/SvEv * C57BL/6 * CBA
abnormal embryonic epiblast morphology J:131055
abnormal primitive streak morphology J:131055
absent mesoderm J:131055
Eomestm1Rob/Eomestm1.1Rob
Tg(T-cre)1Lwd/0
involves: 129S/SvEv * C3H * C57BL/6 * CBA
normal embryo phenotype J:131055
Eomestm1Rob/Eomestm1Rob
involves: 129S/SvEv
no abnormal phenotype detected J:131055
Eomestm1Rob/Eomestm1Rob
Sox1tm1(cre)Take/0
involves: 129S/SvEv * C57BL/6 * CBA
abnormal axon guidance J:138764
abnormal dentate gyrus morphology J:138764
abnormal neuron apoptosis J:138764
abnormal neuronal precursor proliferation J:138764
abnormal olfactory bulb morphology J:138764
absent anterior commissure J:138764
decreased brain size J:138764
decreased grip strength J:138764
hyperactivity J:138764
increased aggression towards humans J:138764
increased aggression towards mice J:138764
small olfactory bulb J:138764
thin cerebral cortex J:138764
Eomestm1Rob/Eomestm2.1Rob
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S/SvEv * C57BL/6 * CBA
abnormal embryonic epiblast morphology J:154785
abnormal primitive streak morphology J:154785
failure to gastrulate J:154785
Eomestm1Srnr/Eomestm1Srnr
Tg(Cd4-cre)1Cwi/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2
decreased memory T cell number J:137655
normal immune system phenotype J:137655
Eomestm1Whk/Eomestm1Whk
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6J
no abnormal phenotype detected J:130570
Eomestm2.1Rob/Eomestm2.1Rob
involves: 129S/SvEv * C57BL/6
embryonic lethality between implantation and placentation, complete penetrance J:154785

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last database update
07/16/2019
MGI 6.14
The Jackson Laboratory