49 phenotypes from 11 alleles in 12 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Eomestm1.1(cre/ERT2)Sjar/Eomes+ involves: 129S/SvEv	no abnormal phenotype detected	J:198846
Eomestm1.1(cre/ERT2)Sjar/Eomestm1.1(cre/ERT2)Sjar involves: 129S/SvEv	embryonic lethality between implantation and placentation	J:198846
Eomestm1.1Bflu/Eomestm1.1Bflu Tg(Cd4-cre)1Cwi/0 involves: C57BL/6 * DBA/2 * SJL	abnormal leukocyte migration	J:163822
	decreased memory T cell number	J:163822
	increased tumor incidence	J:163822
Eomestm1.1Rob/Eomestm1.1Rob involves: 129S/SvEv * C57BL/6 * CBA	abnormal trophoblast layer morphology	J:131055
	embryonic lethality between implantation and somite formation, complete penetrance	J:131055
Eomestm1.1Whk/Eomestm1.1Whk Tg(Six3-cre)69Frty/0 involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 * DBA/2	abnormal optic nerve morphology	J:130570
	abnormal retina ganglion cell morphology	J:130570
	decreased retina ganglion cell number	J:130570
	increased retina apoptosis	J:130570
	thin retina ganglion layer	J:130570
Eomestm1Apr/Eomes+ involves: C57BL/6	decreased memory T cell number	J:112679
	decreased NK cell number	J:112679
Eomestm1Apr/Eomestm1Apr Not Specified	abnormal anterior primitive streak morphology	J:60897
	abnormal egg cylinder morphology	J:60897
	abnormal primitive streak elongation	J:60897
	abnormal trophoblast layer morphology	J:60897
	absent mesoderm	J:60897
	absent primitive node	J:60897
	embryonic growth arrest	J:60897
	embryonic lethality between implantation and somite formation, complete penetrance	J:60897
Eomestm1b(EUCOMM)Wtsi/Eomes+ C57BL/6N-Eomestm1b(EUCOMM)Wtsi/H	decreased bone mineral content	J:211773
	decreased circulating creatinine level	J:211773
	decreased lean body mass	J:211773
	increased total body fat amount	J:211773
Eomestm1b(EUCOMM)Wtsi/Eomestm1b(EUCOMM)Wtsi C57BL/6N-Eomestm1b(EUCOMM)Wtsi/H	embryonic lethality prior to organogenesis	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Eomestm1Jrt/Eomestm1Jrt either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * ICR)	absent trophectoderm	J:98502
	absent trophoblast giant cells	J:98502
	embryonic growth arrest	J:98502
	embryonic lethality before implantation, complete penetrance	J:98502
	failure of embryo implantation	J:98502
Eomestm1Rob/Eomestm1.1Rob Edil3Tg(Sox2-cre)1Amc/Edil3+ involves: 129S/SvEv * C57BL/6 * CBA	abnormal embryonic epiblast morphology	J:131055
	abnormal primitive streak morphology	J:131055
	absent mesoderm	J:131055
Eomestm1Rob/Eomestm1.1Rob Tg(T-cre)1Lwd/0 involves: 129S/SvEv * C3H * C57BL/6 * CBA	normal embryo phenotype	J:131055
Eomestm1Rob/Eomestm1Rob involves: 129S/SvEv	no abnormal phenotype detected	J:131055
Eomestm1Rob/Eomestm1Rob Sox1tm1(cre)Take/0 involves: 129S/SvEv * C57BL/6 * CBA	abnormal axon guidance	J:138764
	abnormal dentate gyrus morphology	J:138764
	abnormal neuron apoptosis	J:138764
	abnormal neuronal precursor proliferation	J:138764
	abnormal olfactory bulb morphology	J:138764
	absent anterior commissure	J:138764
	decreased brain size	J:138764
	decreased grip strength	J:138764
	increased aggression towards humans	J:138764
	increased aggression towards mice	J:138764
	increased exploration in new environment	J:138764
	small olfactory bulb	J:138764
	thin cerebral cortex	J:138764
Eomestm1Rob/Eomestm2.1Rob Edil3Tg(Sox2-cre)1Amc/Edil3+ involves: 129S/SvEv * C57BL/6 * CBA	abnormal embryonic epiblast morphology	J:154785
	abnormal primitive streak morphology	J:154785
	failure to gastrulate	J:154785
Eomestm1Srnr/Eomestm1Srnr Tg(Cd4-cre)1Cwi/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2	decreased memory T cell number	J:137655
	normal immune system phenotype	J:137655
Eomestm1Whk/Eomestm1Whk involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6J	no abnormal phenotype detected	J:130570
Eomestm2.1Rob/Eomestm2.1Rob involves: 129S/SvEv * C57BL/6	embryonic lethality between implantation and placentation, complete penetrance	J:154785