69 phenotypes from 7 alleles in 11 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Eportm1.1(EGFP/icre)Uk/Epor+ Rasa3tm1.1Llp/Rasa3tm1.1Llp involves: 129S1/SvImJ * BALB/cJ * C57BL/6J	normal hematopoietic system phenotype	J:301035
Eportm1.1(EGFP/icre)Uk/Epor+ Rasa3tm1.1Llp/Rasa3tm1.3Llp involves: 129S1/SvImJ * BALB/cJ * C57BL/6J	normal hematopoietic system phenotype	J:301035
Rasa3hlb381/? C57BL/6J-Rasa3hlb381/J	thrombocytopenia	J:82961
Rasa3hlb381/Rasa3hlb381 C57BL/6J-Rasa3hlb381/J	abnormal platelet physiology	J:221899
	decreased leukocyte cell number	J:221899, J:301035
	enlarged spleen	J:221899
	increased mean platelet volume	J:221899
	increased megakaryocyte cell number	J:221899
	increased spleen weight	J:301035
	normal mortality/aging	J:221899
	reticulocytosis	J:301035
	thrombocytopenia	J:221899, J:301035
Rasa3scat/Rasa3+ involves: BALB/cBy	maternal effect	J:14198
Rasa3scat/Rasa3scat B6.CBy-Rasa3scat/Llp	embryonic lethality, complete penetrance	J:301035
Rasa3scat/Rasa3scat involves: BALB/cBy	abnormal erythropoiesis	J:186485
	abnormal megakaryocyte differentiation	J:186485
	abnormal megakaryocyte morphology	J:186485
	abnormal pregnancy	J:10670
	abnormal spleen morphology	J:186485
	anemia	J:186485
	anisocytosis	J:186485
	bruising	J:10670, J:186485
	decreased B cell number	J:186485
	decreased birth body size	J:186485
	decreased bone marrow cell number	J:186485
	decreased CD4-positive, alpha-beta T cell number	J:186485
	decreased CD8-positive, alpha-beta T cell number	J:186485
	decreased leukocyte cell number	J:186485
	decreased mean corpuscular hemoglobin	J:186485
	decreased T cell number	J:186485
	enlarged spleen	J:186485
	hemolysis	J:186485
	hyperlipidemia	J:186485
	increased circulating bilirubin level	J:186485
	increased megakaryocyte cell number	J:186485
	increased spleen red pulp amount	J:186485
	internal hemorrhage	J:10670
	maternal effect	J:14198
	pale spleen	J:186485
	pallor	J:10670, J:186485
	petechiae	J:10670
	poikilocytosis	J:186485
	polychromatophilia	J:186485
	premature death	J:10670
	prenatal lethality, incomplete penetrance	J:14198, J:186485
	preweaning lethality, incomplete penetrance	J:10670
	reticulocytosis	J:186485
	thrombocytopenia	J:186485
Rasa3scat/Rasa3scat involves: BALB/cBy * BALB/cByJ	abnormal cell cycle checkpoint function	J:281271
	abnormal erythroblast morphology	J:281271
	abnormal erythropoiesis	J:281271
	decreased apoptosis	J:281271
	decreased erythrocyte cell number	J:301035
	decreased hematocrit	J:301035
	decreased hemoglobin content	J:301035
	decreased leukocyte cell number	J:301035
	decreased mean corpuscular hemoglobin concentration	J:301035
	increased hemoglobin concentration distribution width	J:301035
	increased mean corpuscular volume	J:301035
	increased mean platelet volume	J:301035
	increased red blood cell distribution width	J:301035
	increased spleen weight	J:301035
	oxidative stress	J:281271
	reticulocytosis	J:301035
	thrombocytopenia	J:301035
Rasa3tm1.1Llp/Rasa3tm1.1Llp Tg(Mx1-cre)1Cgn/? involves: 129S1/SvImJ * C57BL/6J * CBA/J	abnormal erythropoiesis	J:301035
	anemia	J:301035
	anisocytosis	J:301035
	bone marrow failure	J:301035
	decreased erythrocyte cell number	J:301035
	decreased hematocrit	J:301035
	decreased hemoglobin content	J:301035
	decreased leukocyte cell number	J:301035
	hemolysis	J:301035
	increased circulating bilirubin level	J:301035
	increased circulating lactate dehydrogenase level	J:301035
	increased mean corpuscular volume	J:301035
	increased mean platelet volume	J:301035
	increased megakaryocyte-erythroid progenitor cell number	J:301035
	increased red blood cell distribution width	J:301035
	increased spleen weight	J:301035
	pancytopenia	J:301035
	poikilocytosis	J:301035
	reticulocytosis	J:301035
	thrombocytopenia	J:301035
Rasa3tm1.1Llp/Rasa3tm1.1Llp Tg(Tek-cre)1Ywa/? involves: 129S1/SvImJ * C57BL/6J * SJL/J	abnormal embryonic hematopoiesis	J:301035
	embryonic lethality prior to tooth bud stage	J:301035
	hemorrhage	J:301035
Rasa3tm1.1Llp/Rasa3tm1.1Llp Tg(Vav1-cre)1Cgp/? involves: 129S1/SvImJ * C57BL/6J	abnormal embryonic hematopoiesis	J:301035
	embryonic lethality prior to tooth bud stage	J:301035
	hemorrhage	J:301035
Rasa3tm1.1Llp/Rasa3tm1.3Llp Tg(CMV-cre)1Cgn/? involves: 129S1/SvImJ * BALB/cJ * C57BL/6J	embryonic lethality, complete penetrance	J:301035
Rasa3tm1a(KOMP)J/Rasa3tm1a(KOMP)J Tg(CMV-cre)1Cgn/? (C57BL/6N-Rasa3tm1a(KOMP)J/J x B6.C-Tg(CMV-cre)1Cgn/J)F2	embryonic lethality, complete penetrance	J:301035
	hemorrhage	J:301035
	pale liver	J:301035
	pallor	J:301035
Rasa3tm1b(KOMP)J/Rasa3+ C57BL/6N-Rasa3tm1b(KOMP)J/J	abnormal sleep behavior	J:211773
	decreased circulating glucose level	J:211773
	decreased exploration in new environment	J:211773
	increased heart weight	J:211773
Rasa3tm1b(KOMP)J/Rasa3tm1b(KOMP)J C57BL/6N-Rasa3tm1b(KOMP)J/J	prenatal lethality prior to heart atrial septation	J:211773
	preweaning lethality, complete penetrance	J:211773
Rasa3tm1Shiw/Rasa3tm1Shiw Not Specified	abnormal embryo development	J:120930
	abnormal vascular endothelial cell development	J:120930
	edema	J:120930
	hemorrhage	J:120930
	lethality throughout fetal growth and development, complete penetrance	J:120930