Birc3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Birc3
baculoviral IAP repeat-containing 3
MGI:1197007

27 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Birc3^tm1Jda/Birc3^tm1Jda B6.Cg-Birc3^tm1Jda	abnormal gut-associated lymphoid tissue morphology	J:166899
	abnormal lymphocyte cell number	J:166899
	decreased B cell apoptosis	J:166899
	decreased follicular B cell number	J:166899
	decreased IgG1 level	J:166899
	decreased immature B cell number	J:166899
	enlarged mesenteric lymph nodes	J:166899
	increased B cell number	J:166899
	increased B cell proliferation	J:166899
	increased IgA level	J:166899
	increased IgG3 level	J:166899
	increased IgM level	J:166899
	increased marginal zone B cell number	J:166899
	increased T cell number	J:166899
	lymph node hyperplasia	J:166899
Birc3^tm1Jda/Birc3^tm1Jda involves: 129 * C57BL/6	increased interferon-gamma secretion	J:199221
Birc3^tm1Jda/Birc3^tm1Jda involves: 129 * C57BL/6	increased T cell proliferation	J:199221
Birc3^tm1Rgk/Birc3^tm1Rgk B6.129X1-Birc3^tm1Rgk	abnormal cytokine secretion	J:144012
	abnormal immune cell physiology	J:144012
	abnormal interleukin-1 beta secretion	J:144012
	abnormal interleukin-12 secretion	J:144012
	abnormal leukocyte cell number	J:144012
	abnormal macrophage physiology	J:144012
	abnormal T cell physiology	J:144012
	abnormal tumor necrosis factor secretion	J:144012
	decreased macrophage cell number	J:144012
	decreased susceptibility to endotoxin shock	J:144012

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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