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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Nus1
NUS1 dehydrodolichyl diphosphate synthase subunit
MGI:1196365
13 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sortm1(cre/ERT2)Tyj
Nus1tm1.1Qrm/Nus1tm1.1Qrm
involves: 129 * C57BL/6 * SJL
abnormal lipid homeostasis J:243753
hepatic steatosis J:243753
increased liver free fatty acids level J:243753
normal increased liver triglyceride level J:243753
Nus1tm1.1Qrm/Nus1tm1.1Qrm
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
involves: 129 * C57BL/6 * DBA * SJL
abnormal circulating cholesterol level J:243753
abnormal lipid homeostasis J:243753
decreased liver cholesterol level J:243753
increased circulating free fatty acid level J:243753
increased circulating triglyceride level J:243753
increased liver free fatty acids level J:243753
increased liver triglyceride level J:243753
Nus1tm1.1Wcsa/Nus1tm1.1Wcsa
involves: 129S4/SvJae
embryonic lethality, complete penetrance J:215785
Nus1tm1Wcsa/Nus1tm1.1Wcsa
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ
abnormal cell physiology J:215785
abnormal cellular cholesterol metabolism J:215785
increased sensitivity to induced cell death J:215785

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/09/2019
MGI 6.14
The Jackson Laboratory