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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Casz1
castor zinc finger 1
MGI:1196251
43 phenotypes from 4 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Casz1Gt(CJ0565)Wtsi/Casz1Gt(CJ0565)Wtsi
involves: 129P2/OlaHsd * C57BL/6
abnormal blood circulation J:242127
abnormal fetal cardiomyocyte morphology J:242127
abnormal heart development J:242127
abnormal heart shape J:242127
abnormal interventricular septum morphology J:242127
abnormal lymphatic vessel morphology J:242127
abnormal myocardium compact layer morphology J:242127
abnormal sarcomere morphology J:242127
abnormal Z line morphology J:242127
congestive heart failure J:242127
decreased fetal cardiomyocyte proliferation J:242127
enlarged lymphatic vessel J:242127
lethality throughout fetal growth and development, complete penetrance J:242127
liver vascular congestion J:242127
myocardium hypoplasia J:242127
nuchal edema J:242127
subcutaneous edema J:242127
thin interventricular septum J:242127
thin myocardium J:242127
ventricular myocardium compact layer hypoplasia J:242127
ventricular septal defect J:242127
Casz1tm1.1Flc/Casz1+
Nkx2-5tm1(cre)Rjs/Nkx2-5+
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL
normal no abnormal phenotype detected J:221324
Casz1tm1.1Flc/Casz1tm1.1Flc
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * CBA * SJL
abnormal heart development J:221324
embryonic lethality during organogenesis, complete penetrance J:221324
heart hypoplasia J:221324
thin ventricular wall J:221324
ventricular septal defect J:221324
Casz1tm1.1Flc/Casz1tm1.1Flc
Isl1tm1(cre)Tmj/Isl1+
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * C57BL/6J * SJL
abnormal heart right ventricle morphology J:221324
abnormal heart shape J:221324
decreased mitotic index J:221324
heart right ventricle hypoplasia J:221324
lethality throughout fetal growth and development, complete penetrance J:221324
Casz1tm1.1Flc/Casz1tm1.1Flc
Nkx2-5tm1(cre)Rjs/Nkx2-5+
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL
abnormal cell cycle checkpoint function J:221324
abnormal fetal cardiomyocyte morphology J:221324
abnormal fetal cardiomyocyte physiology J:221324
abnormal heart apex morphology J:221324
abnormal heart development J:221324
abnormal heart left ventricle morphology J:221324
abnormal heart shape J:221324
abnormal heart ventricle morphology J:221324
abnormal interventricular septum morphology J:221324
decreased fetal cardiomyocyte proliferation J:221324
decreased mitotic index J:221324
dilated heart right atrium J:221324
distended pericardium J:221324
edema J:221324
embryonic lethality during organogenesis, complete penetrance J:221324
enlarged heart right atrium J:221324
heart hypoplasia J:221324
hemorrhage J:221324
perimembraneous ventricular septal defect J:221324
poor circulation J:221324
thin myocardium J:221324
thin ventricular wall J:221324
trabecula carnea hypoplasia J:221324
Casz1tm1b(EUCOMM)Hmgu/Casz1+
C57BL/6N-Casz1tm1b(EUCOMM)Hmgu/H
persistence of hyaloid vascular system J:211773
Casz1tm1b(EUCOMM)Hmgu/Casz1tm1b(EUCOMM)Hmgu
C57BL/6N-Casz1tm1b(EUCOMM)Hmgu/H
preweaning lethality, complete penetrance J:211773
Casz1tm2(cre/ERT2)Flc/Casz1+
involves: 129P2/OlaHsd
normal no abnormal phenotype detected J:221324

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/05/2019
MGI 6.14
The Jackson Laboratory