Terf2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Terf2
telomeric repeat binding factor 2
MGI:1195972

33 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Ercc4^tm1Fwa/Ercc4^tm1Fwa Tg(KRT5-Terf2)PMBlas/Y involves: 129S6/SvEvTac * C57BL/6 * CBA	abnormal telomere morphology	J:102653
Terc^tm1Rdp/Terc^tm1Rdp Tg(KRT5-Terf2)PMBlas/Y involves: 129/Sv * C57BL/6 * CBA * SJL	decreased telomere length	J:102653
	dry skin	J:102653
	focal hair loss	J:102653
Tg(KRT5-Terf2)PMBlas/Y involves: C57BL/6 * CBA	abnormal DNA repair	J:102653
	abnormal epidermal pigmentation	J:102653
	abnormal keratinocyte physiology	J:102653
	abnormal skin morphology	J:102653
	abnormal telomere morphology	J:102653
	chromosomal instability	J:102653
	decreased keratinocyte proliferation	J:102653
	decreased telomere length	J:102653
	dry skin	J:102653
	epidermal atrophy	J:102653
	epidermal hyperplasia	J:102653
	focal dorsal hair loss	J:102653
	hair follicle degeneration	J:102653
	increased cellular sensitivity to alkylating agents	J:102653
	increased cellular sensitivity to ultraviolet irradiation	J:102653
	increased ear pigmentation	J:102653
	increased foot pigmentation	J:102653
	increased incidence of tumors by UV-induction	J:102653
	increased keratoacanthoma incidence	J:102653
	increased sensitivity to skin irradiation	J:102653
	increased skin pigmentation	J:102653
	increased skin squamous cell carcinoma incidence	J:102653
	increased skin tumor incidence	J:102653
	increased tail pigmentation	J:102653
	induced chromosome breakage	J:102653
	premature aging	J:102653
	prenatal lethality, incomplete penetrance	J:102653
	sebaceous gland atrophy	J:102653
	skin hyperplasia	J:102653
	skin photosensitivity	J:102653
Tg(KRT5-Terf2)PMBlas/Y Tg(KRT5-Tert)8043Blas/0 involves: C57BL/6 * CBA * DBA/2	decreased telomere length	J:102653
	increased skin pigmentation	J:102653
Tg(KRT5-Terf2)PNBlas/0 involves: C57BL/6 * CBA	decreased telomere length	J:102653
	increased ear pigmentation	J:102653
	increased foot pigmentation	J:102653
	increased skin pigmentation	J:102653
	increased tail pigmentation	J:102653
	normal mortality/aging	J:102653
	normal neoplasm	J:102653
Tg(KRT5-Terf2)POBlas/0 involves: C57BL/6 * CBA	abnormal DNA repair	J:102653
	abnormal keratinocyte physiology	J:102653
	chromosomal instability	J:102653
	decreased telomere length	J:102653
	increased cellular sensitivity to alkylating agents	J:102653
	increased cellular sensitivity to ultraviolet irradiation	J:102653
	increased ear pigmentation	J:102653
	increased foot pigmentation	J:102653
	increased incidence of tumors by UV-induction	J:102653
	increased keratoacanthoma incidence	J:102653
	increased sensitivity to skin irradiation	J:102653
	increased skin pigmentation	J:102653
	increased skin squamous cell carcinoma incidence	J:102653
	increased skin tumor incidence	J:102653
	increased tail pigmentation	J:102653
	induced chromosome breakage	J:102653
	normal mortality/aging	J:102653
	skin photosensitivity	J:102653

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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