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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Rnf2
ring finger protein 2
MGI:1101759
19 phenotypes from 4 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
Rnf2tm1Mvi/Rnf2tm1Mvi
involves: 129S/Sv * 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal neuron differentiation J:154927
Polr2atm1(cre/ERT2)Bbd/Polr2a+
Rnf2tm1Mvi/Rnf2tm1Mvi
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/10 * SJL 		abnormal bone marrow cell morphology/development J:130397
abnormal common myeloid progenitor cell morphology J:130397
decreased B cell number J:130397
Rnf2tm1Hko/Rnf2tm1Hko
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal sternum ossification J:79851
cervical vertebral transformation J:79851
thoracic vertebral transformation J:79851
Rnf2tm1Mvi/Rnf2tm1Mvi
Tg(Mx1-cre)1Cgn/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/10 * CBA 		abnormal B cell differentiation J:130397
abnormal bone marrow cell morphology/development J:130397
abnormal common myeloid progenitor cell morphology J:130397
decreased B cell number J:130397
decreased bone marrow cell number J:130397
decreased erythrocyte cell number J:130397
decreased monocyte cell number J:130397
thrombocytosis J:130397
Rnf2tm1Mvi/Rnf2tm1Mvi
Tg(Nes-cre/ERT2)5-1Kag/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal neuron differentiation J:154927
Rnf2tm1Mvl/Rnf2tm1Mvl
either: (involves: 129/Ola) or (involves: 129/Ola * FVB) 		abnormal embryonic epiblast morphology J:82399
abnormal mesoderm development J:82399
embryonic growth arrest J:82399
embryonic lethality during organogenesis, complete penetrance J:82399
failure to gastrulate J:82399
Rnf2tm3Hko/Rnf2tm3Hko
involves: 129S1/Sv * 129X1/SvJ 		normal reproductive system phenotype J:204987
normal skeleton phenotype J:204987
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory