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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Slc18a3
solute carrier family 18 (vesicular monoamine), member 3
MGI:1101061
24 phenotypes from 4 alleles in 2 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Chat/Slc18a3tm1.1Vpra/Slc18a3+
involves: 129S4/SvJae * C57BL/6J
abnormal miniature endplate potential J:171696
normal behavior/neurological phenotype J:171696
increased acetylcholine level J:153908
Chat/Slc18a3tm1.1Vpra/Chat/Slc18a3tm1.1Vpra
involves: 129S4/SvJae * C57BL/6J
abnormal miniature endplate potential J:153908
abnormal motor neuron innervation pattern J:153908
abnormal neuromuscular synapse morphology J:153908
abnormal skeletal muscle morphology J:153908
abnormal synaptic acetylcholine release J:153908
cyanosis J:153908
hypotonia J:153908
increased acetylcholine level J:153908
increased motor neuron number J:153908
kyphosis J:153908
neonatal lethality, complete penetrance J:153908
skeletal muscle atrophy J:153908
skeletal muscle fiber atrophy J:153908
Chat/Slc18a3tm1.1Vpra/Chat/Slc18a3tm1.1Vpra
Tg(Chat-COP4*H134R/EYFP,Slc18a3)6Gfng/0
involves: 129S4/SvJae * C57BL/6 * CBA
normal mortality/aging J:197166
Chat/Slc18a3tm1.2Vpra/Chat/Slc18a3tm1.2Vpra
involves: 129S4/SvJae * C57BL/6J
normal behavior/neurological phenotype J:171696
Chat/Slc18a3tm1Vpra/Chat/Slc18a3tm1.1Vpra
involves: 129S4/SvJae * C57BL/6J
abnormal miniature endplate potential J:171696
normal behavior/neurological phenotype J:171696
hyperactivity J:171696
increased vertical activity J:171696
Chat/Slc18a3tm1Vpra/Chat/Slc18a3tm1Vpra
involves: 129S4/SvJae * C57BL/6J
abnormal miniature endplate potential J:171696
normal behavior/neurological phenotype J:171696
hyperactivity J:171696
Slc18a3tm1Mca/Slc18a3+
involves: 129S4/SvJae * C57BL/6J
abnormal miniature endplate potential J:137284
abnormal object recognition memory J:137284
abnormal social investigation J:137284
abnormal synaptic acetylcholine release J:137284
normal behavior/neurological phenotype J:137284
impaired coordination J:137284
Slc18a3tm1Mca/Slc18a3tm1Mca
involves: 129S4/SvJae * C57BL/6J
abnormal endplate potential J:137284
abnormal miniature endplate potential J:137284
abnormal social investigation J:137284
abnormal synaptic acetylcholine release J:137284
decreased grip strength J:137284
impaired coordination J:137284
impaired exercise endurance J:137284
increased susceptibility to pharmacologically induced seizures J:136620

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory