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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Fgf10
fibroblast growth factor 10
MGI:1099809
43 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Fgf3tm1Mrc/Fgf3+
Fgf10tm1Wss/Fgf10tm1Wss
involves: 129S7/SvEvBrd * 129X1/SvJ
small otic vesicle J:83659
Fgf3tm1Mrc/Fgf3tm1Mrc
Fgf10tm1Wss/Fgf10+
involves: 129S7/SvEvBrd * 129X1/SvJ
abnormal otic vesicle development J:83659
small otic vesicle J:83659
Fgf3tm1Mrc/Fgf3tm1Mrc
Fgf10tm1Wss/Fgf10tm1Wss
involves: 129S7/SvEvBrd * 129X1/SvJ
absent inner ear J:83659
absent limbs J:83659
absent otic vesicle J:83659
curly tail J:83659
short tail J:83659
Fgf3tm1Sng/Fgf3tm1Sng
Fgf10tm1Ska/Fgf10tm1Ska
involves: 129P2/OlaHsd * C57BL/6 * CBA
abnormal ear development J:87221
absent vestibulocochlear ganglion J:87221
embryonic lethality during organogenesis, complete penetrance J:87221
small otic vesicle J:87221
Fgf10tm1.1(cre/ERT2)Sbel/Fgf10tm1Sms
Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+
involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6
abnormal cecum development J:187831
abnormal lung bud morphology J:187831
interdigital webbing J:187831
Fgf10tm1.1Sms/Fgf10tm1.1Sms
Fgf3tm1.1Sms/Fgf3tm1.1Sms
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * BALB/cJ
absent limbs J:160254
absent otic vesicle J:160254
short tail J:160254
small otic vesicle J:160254
Fgf10tm1.2Sms/Fgf10tm1.2Sms
Fgf3tm1.2Sms/Fgf3tm1.2Sms
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
no abnormal phenotype detected J:160254
Fgf10tm1Ska/Fgf10+
Fgf8tm1Moon/Fgf8tm1Moon
Mesp1tm2(cre)Ysa/Mesp1+
involves: C57BL/6NCrlj * CBA/JNCrlj
aberrant origin of the right subclavian artery J:170879
abnormal aortic arch morphology J:170879
abnormal cardiac outflow tract development J:170879
abnormal cardiovascular development J:170879
abnormal common carotid artery morphology J:170879
abnormal fourth pharyngeal arch artery morphology J:170879
abnormal pharyngeal arch artery morphology J:170879
abnormal sixth pharyngeal arch artery morphology J:170879
abnormal third pharyngeal arch artery morphology J:170879
decreased heart right ventricle size J:170879
double outlet right ventricle J:170879
right aortic arch J:170879
second pharyngeal arch hypoplasia J:170879
third pharyngeal arch hypoplasia J:170879
ventricular septal defect J:170879
Fgf10tm1Ska/Fgf10tm1Ska
Fgf8tm1Moon/Fgf8tm1Moon
Mesp1tm2(cre)Ysa/Mesp1+
involves: C57BL/6NCrlj * CBA/JNCrlj
aberrant origin of the right subclavian artery J:170879
abnormal aortic arch morphology J:170879
abnormal cardiac epithelial to mesenchymal transition J:170879
abnormal cardiac neural crest cell migration J:170879
abnormal cardiac outflow tract development J:170879
abnormal cardiovascular development J:170879
abnormal common carotid artery morphology J:170879
abnormal fourth pharyngeal arch artery morphology J:170879
abnormal pharyngeal arch artery morphology J:170879
abnormal sixth pharyngeal arch artery morphology J:170879
abnormal third pharyngeal arch artery morphology J:170879
decreased heart right ventricle size J:170879
double outlet right ventricle J:170879
second pharyngeal arch hypoplasia J:170879
third pharyngeal arch hypoplasia J:170879
ventricular septal defect J:170879
Fgf10tm1Ska/Fgf10tm1Sms
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
Twist2tm1(cre)Dor/Twist2+
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 * CBA
abnormal lung development J:150706
abnormal lung lobe morphology J:150706
abnormal right lung accessory lobe morphology J:150706
abnormal right lung cranial lobe morphology J:150706
abnormal right lung middle lobe morphology J:150706
impaired branching involved in bronchus morphogenesis J:150706
lung hemorrhage J:150706
pulmonary hypoplasia J:150706
small lung J:150706
small lung lobe J:150706
Fgf10tm1Wss/Fgf10+
Fgfr2tm2Dsn/Fgfr2+
Tg(Pgk1-cre)1Lni/0
involves: 129 * 129X1/SvJ * BALB/c * C57BL/6
abnormal submandibular duct morphology J:119849
decreased submandibular gland size J:119849

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory