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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Hip1
huntingtin interacting protein 1
MGI:1099804
57 phenotypes from 7 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Hip1em1(IMPC)Hmgu/Hip1em1(IMPC)Hmgu
C57BL/6N-Hip1em1(IMPC)Hmgu/Ieg
abnormal cornea morphology J:211773
abnormal gait J:211773
abnormal vertebrae morphology J:211773
corneal opacity J:211773
decreased body length J:211773
decreased circulating creatinine level J:211773
decreased locomotor activity J:211773
decreased vertical activity J:211773
hyperactivity J:211773
increased bone mineral content J:211773
Hip1tm1Hay/Hip1tm1Hay
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal gait J:84278
abnormal motor capabilities/coordination/movement J:84278
abnormal muscle morphology J:84278
decreased body weight J:84278
decreased locomotor activity J:84278
kyphosis J:84278
postnatal growth retardation J:84278
premature death J:84278
short stride length J:84278
tremors J:84278
Hip1tm1Tsr/Hip1+
involves: 129X1/SvJ * C57BL/6
seminiferous tubule degeneration J:72637
Hip1tm1Tsr/Hip1tm1Tsr
involves: 129X1/SvJ * C57BL/6
abnormal seminiferous tubule morphology J:90400
abnormal spermatogenesis J:72637
absent common myeloid progenitor cells J:90400
normal behavior/neurological phenotype J:72637
decreased male germ cell number J:72637
decreased testis weight J:72637
normal hematopoietic system phenotype J:90400
normal homeostasis/metabolism phenotype J:72637
increased male germ cell apoptosis J:72637
multinucleated giant male germ cells J:90400
oligozoospermia J:72637
postnatal lethality, incomplete penetrance J:72637
seminiferous tubule degeneration J:72637
testicular atrophy J:72637
normal vision/eye phenotype J:90400
Hip1tm2.1Tsr/Hip1tm2.1Tsr
involves: 129X1/SvJ
normal hematopoietic system phenotype J:90400
kyphosis J:90400
male infertility J:90400
normal skeleton phenotype J:90400
normal vision/eye phenotype J:90400
Hip1tm2Tsr/Hip1tm2Tsr
involves: 129X1/SvJ * C57BL/6
no abnormal phenotype detected J:90400
Hip1tm3Tsr/Hip1tm3Tsr
involves: 129X1/SvJ * C57BL/6
abnormal spermatid morphology J:90400
absent common myeloid progenitor cells J:90400
normal hematopoietic system phenotype J:90400
lordokyphosis J:90400
microphthalmia J:90400
normal nervous system phenotype J:90400
nuclear cataract J:90400
perinatal lethality, incomplete penetrance J:90400
reduced male fertility J:90400
normal skeleton phenotype J:90400
small lens J:90400
testis degeneration J:90400
weight loss J:90400
Hip1tm4Tsr/Hip1+
involves: 129X1/SvJ * C57BL/6
cataract J:151974
microphthalmia J:151974
Hip1tm4Tsr/Hip1+
Tg(Mx1-cre)1Cgn/0
involves: 129X1/SvJ * C57BL/6 * CBA
abnormal myelopoiesis J:151974
abnormal spleen morphology J:151974
abnormal tumor incidence J:151974
decreased hematopoietic stem cell number J:151974
enlarged spleen J:151974
normal hematopoietic system phenotype J:151974
increased hepatocellular carcinoma incidence J:151974
increased liver tumor incidence J:151974
increased spleen red pulp amount J:151974
increased susceptibility to xenobiotic induced morbidity/mortality J:151974
increased T cell derived lymphoma incidence J:151974

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory