Sptlc1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sptlc1
serine palmitoyltransferase, long chain base subunit 1
MGI:1099431

11 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sptlc1^em1(IMPC)Bay/Sptlc1⁺ C57BL/6N-Sptlc1^em1(IMPC)Bay/BayMmucd	abnormal embryo size	J:211773
	abnormal eye anterior chamber depth	J:211773
	embryonic growth retardation	J:211773
	increased cornea thickness	J:211773
Sptlc1^em1(IMPC)Bay/Sptlc1^em1(IMPC)Bay C57BL/6N-Sptlc1^em1(IMPC)Bay/BayMmucd	preweaning lethality, complete penetrance	J:211773
Sptlc1^{Gt(AD0062)Wtsi}/Sptlc1⁺ involves: 129P2/OlaHsd	normal behavior/neurological phenotype	J:155748
	normal nervous system phenotype	J:155748
	normal reproductive system phenotype	J:155748
Sptlc1^tm1Jia/Sptlc1⁺ B6.Cg-Sptlc1^tm1Jia	abnormal circulating lipid level	J:140627
Sptlc1^tm1Jia/Sptlc1⁺ B6.Cg-Sptlc1^tm1Jia	abnormal lipid level	J:140627
Sptlc1^tm1Jia/Sptlc1^tm1Jia B6.Cg-Sptlc1^tm1Jia	prenatal lethality, complete penetrance	J:140627

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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