Ift81 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ift81
intraflagellar transport 81
MGI:1098597

29 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ift81^{tm1b(EUCOMM)Wtsi}/Ift81⁺ C57BL/6N-Ift81^{tm1b(EUCOMM)Wtsi}/Ieg	abnormal retina blood vessel morphology	J:211773
	abnormal retina morphology	J:211773
	abnormal retina vasculature morphology	J:211773
	decreased grip strength	J:211773
	decreased heart rate	J:211773
	decreased locomotor activity	J:211773
	increased startle reflex	J:211773
	persistence of hyaloid vascular system	J:211773
Ift81^{tm1b(EUCOMM)Wtsi}/Ift81^{tm1b(EUCOMM)Wtsi} C57BL/6N-Ift81^{tm1b(EUCOMM)Wtsi}/Ieg	preweaning lethality, complete penetrance	J:211773
Ift81^{tm1c(EUCOMM)Wtsi}/Ift81^{tm1c(EUCOMM)Wtsi} Tg(Stra8-icre)1Reb/0 involves: C57BL/6 * C57BL/6N * FVB/NJ	abnormal acrosome morphology	J:292151
	abnormal seminiferous tubule epithelium morphology	J:292151
	abnormal sperm axoneme morphology	J:292151
	abnormal sperm fibrous sheath morphology	J:292151
	abnormal sperm flagellum morphology	J:292151
	abnormal sperm head morphology	J:292151
	abnormal sperm midpiece morphology	J:292151
	abnormal sperm mitochondrial sheath morphology	J:292151
	abnormal sperm nucleus morphology	J:292151
	abnormal spermiation	J:292151
	abnormal spermiogenesis	J:292151
	abnormal testis physiology	J:292151
	asthenozoospermia	J:292151
	immotile sperm	J:292151
	kinked sperm flagellum	J:292151
	male infertility	J:292151
	multinucleated giant male germ cells	J:292151
	oligozoospermia	J:292151
	normal reproductive system phenotype	J:292151
	short sperm flagellum	J:292151

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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