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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Hdac2
histone deacetylase 2
MGI:1097691
46 phenotypes from 7 alleles in 9 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Hdac2Gt(W035F03)Joe/Hdac2Gt(W035F03)Joe
involves: 129S2/SvPas
abnormal intestinal mucosa morphology J:152134
abnormal large intestine crypts of Lieberkuhn morphology J:152134
abnormal pelvic girdle bone morphology J:152134
decreased body weight J:152134
decreased brain weight J:152134
decreased intestine length J:152134
decreased survivor rate J:152134
embryonic lethality during organogenesis, incomplete penetrance J:152134
insensitivity to growth hormone J:152134
small testis J:152134
small vertebrae J:152134
Hdac2Gt(W035F03)Joe/Hdac2Gt(W035F03)Joe
Not Specified
abnormal cardiovascular system morphology J:121697
abnormal cardiovascular system physiology J:121697
abnormal fetal cardiomyocyte proliferation J:121697
abnormal myocardial fiber physiology J:121697
abnormal myocardial trabeculae morphology J:121697
abnormal myocardium compact layer morphology J:121697
abnormal myocardium layer morphology J:121697
normal cardiovascular system phenotype J:121697
decreased body size J:121697
diffuse Z line J:121697
enlarged heart J:121697
lethargy J:121697
postnatal lethality, incomplete penetrance J:121697
prenatal lethality, incomplete penetrance J:121697
thick ventricular wall J:121697
Hdac2tm1.1Eno/Hdac2tm1.1Eno
H2afvTg(Wnt1-cre)11Rth/?
involves: 129 * C57BL/6 * CBA
no abnormal phenotype detected J:150709
Hdac2tm1.1Eno/Hdac2tm1.1Eno
Tg(Myh6-cre)2182Mds/?
involves: 129S/SvEv * C57BL/6 * CD-1 * FVB/N
no abnormal phenotype detected J:123173
Hdac2tm1.1Shmc/Hdac2tm1.1Shmc
Tg(Lck-cre)1Cwi/0
involves: 129S7/SvEvBrd
normal immune system phenotype J:194769
Hdac2tm1.2Eno/Hdac2tm1.2Eno
involves: 129S/SvEv * C57BL/6 * CD-1
abnormal fetal cardiomyocyte proliferation J:123173
abnormal heart right ventricle morphology J:123173
cyanosis J:123173
decreased heart rate J:123173
increased cardiomyocyte apoptosis J:123173
neonatal lethality, complete penetrance J:123173
thick interventricular septum J:123173
Hdac2tm1.2Pmt/Hdac2tm1.2Pmt
involves: 129P2/OlaHsd * C57BL/6 * FVB/N
decreased birth body size J:157903
perinatal lethality, incomplete penetrance J:157903
Hdac2tm1.2Rdp/Hdac2tm1.2Rdp
involves: 129S4/SvJae * C57BL/6 * FVB/N
abnormal dentate gyrus morphology J:148391
abnormal hippocampus CA1 region morphology J:148391
abnormal hippocampus pyramidal cell morphology J:148391
decreased body size J:148391
enhanced contextual conditioning behavior J:148391
enhanced long term potentiation J:148391
prenatal lethality, incomplete penetrance J:148391
reduced fertility J:148391
Hdac2tm1Lex/Hdac2+
involves: 129S5/SvEvBrd * C57BL/6
abnormal eye electrophysiology J:214041
abnormal total retina thickness J:214041
decreased susceptilbility to retinal ischemic injury J:214041
Hdac2tm1Lex/Hdac2tm1Lex
involves: 129S5/SvEvBrd * C57BL/6
abnormal heart morphology J:214041
neonatal lethality, complete penetrance J:214041

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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory