Cx3cl1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cx3cl1
C-X3-C motif chemokine ligand 1
MGI:1097153

6 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Apoe^tm1Unc/Apoe^tm1Unc Ccr2^tm1Ifc/Ccr2^tm1Ifc Cx3cl1^tm1Lira/Cx3cl1^tm1Lira B6.Cg-Apoe^tm1Unc Cx3cl1^tm1Lira Ccr2^tm1Ifc	decreased monocyte cell number	J:153310
	decreased susceptibility to atherosclerosis	J:153310
Apoe^tm1Unc/Apoe^tm1Unc Cx3cl1^tm1Sgs/Cx3cl1^tm1Sgs B6.129-Apoe^tm1Unc Cx3cl1^tm1Sgs	decreased susceptibility to atherosclerosis	J:95279
	impaired macrophage chemotaxis	J:95279
	increased macrophage derived foam cell number	J:95279
Cx3cl1^tm1Sgs/Cx3cl1^tm1Sgs Ldlr^tm1Her/Ldlr⁺ involves: B6.129S4-Cx3cl1^tm1Sgs * B6.129S7-Ldlr^tm1Her/J	decreased circulating cholesterol level	J:95279
	decreased circulating LDL cholesterol level	J:95279
	decreased susceptibility to atherosclerosis	J:95279
Cx3cl1^tm1Sgs/Cx3cl1^tm1Sgs Ldlr^tm1Her/Ldlr^tm1Her involves: B6.129S4-Cx3cl1^tm1Sgs * B6.129S7-Ldlr^tm1Her/J	decreased circulating cholesterol level	J:95279
	decreased circulating LDL cholesterol level	J:95279
	decreased susceptibility to atherosclerosis	J:95279
	impaired macrophage chemotaxis	J:95279

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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