Cxcl5 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cxcl5
C-X-C motif chemokine ligand 5
MGI:1096868

15 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cxcl5^{em1(IMPC)Kmpc}/Cxcl5^{em1(IMPC)Kmpc} C57BL/6NTac-Cxcl5^{em1(IMPC)Kmpc}/Kmpc	decreased startle reflex	J:211773
	hyperactivity	J:211773
Cxcl5^tm1.1Mkch/Cxcl5^tm1.1Mkch B6.129P2-Cxcl5^tm1.1Mkch	decreased interferon-alpha secretion	J:208901
	decreased interleukin-1 alpha secretion	J:208901
	decreased interleukin-6 secretion	J:208901
	decreased neutrophil cell number	J:208901
	decreased susceptibility to bacterial infection	J:208901
	decreased susceptibility to bacterial infection induced morbidity/mortality	J:208901
	decreased tumor necrosis factor secretion	J:208901
	normal immune system phenotype	J:208901
Cxcl5^tm1Gscw/Cxcl5^tm1Gscw involves: 129	abnormal circulating chemokine level	J:162629
	abnormal neutrophil physiology	J:162629
	decreased circulating interleukin-6 level	J:162629
	decreased susceptibility to bacterial infection	J:162629
	decreased susceptibility to bacterial infection induced morbidity/mortality	J:162629
	decreased susceptibility to endotoxin shock	J:162629
	increased granulocyte number	J:162629

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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