Mesp2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mesp2
mesoderm posterior 2
MGI:1096325

23 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Lfng^tm1Rjo/Lfng^tm1Rjo Mesp2^{tm15.1(Lfng)Ysa}/Mesp2⁺ involves: 129S7/SvEvBrd	abnormal dorsal-ventral polarity of the somites	J:159983
	abnormal somite development	J:159983
Mesp1/Mesp2^tm1Ysa/Mesp1⁺ Mesp1/Mesp2^tm1Ysa/Mesp2^tm8Ysa involves: C57BL/6 * CBA * ICR	rib fusion	J:119678
Mesp1/Mesp2^tm1Ysa/Mesp1⁺ Mesp1/Mesp2^tm1Ysa/Mesp2^tm9Ysa involves: C57BL/6 * CBA * ICR	rib fusion	J:119678
Mesp1/Mesp2^tm1Ysa/Mesp1⁺ Mesp1/Mesp2^tm1Ysa/Mesp2^tm10Ysa involves: C57BL/6 * CBA * ICR	abnormal vertebrae morphology	J:119678
	decreased body length	J:119678
	fusion of vertebral arches	J:119678
Mesp1/Mesp2^tm1Ysa/Mesp1⁺ Mesp1/Mesp2^tm1Ysa/Mesp2^tm11Ysa involves: C57BL/6 * CBA * ICR	abnormal vertebrae morphology	J:119678
	vertebral fusion	J:119678
Mesp1^tm3Ysa/Mesp1^tm3Ysa Mesp2^tm3(cre)Ysa/Mesp2^tm3(cre)Ysa involves: C57BL/6 * CBA	abnormal embryo development	J:62984
	abnormal embryonic growth/weight/body size	J:62984
	abnormal heart morphology	J:62984
	embryonic lethality during organogenesis, complete penetrance	J:62984
Mesp2^tm1Ysa/Mesp2^{tm7(mespb)Ysa} involves: C57BL/6 * CBA	abnormal rostral-caudal patterning of the somites	J:75945
	abnormal somite border morphology	J:75945
	abnormal somite development	J:75945
	rib fusion	J:75945
	vertebral fusion	J:75945
Mesp2^tm1Ysa/Mesp2^{tm7.1(mespb)Ysa} involves: C57BL/6 * CBA	abnormal rostral-caudal patterning of the somites	J:75945
	abnormal somite border morphology	J:75945
	abnormal somite development	J:75945
	neonatal lethality, complete penetrance	J:75945
	rib fusion	J:75945
	vertebral fusion	J:75945
Mesp2^tm1Ysa/Mesp2^tm10Ysa Gt(ROSA)26Sor/? involves: 129 * C57BL/6 * CBA	failure of somite differentiation	J:120635
Mesp2^{tm2(Mesp1)Ysa}/Mesp2^{tm2(Mesp1)Ysa} involves: C57BL/6 * CBA	abnormal axial skeleton morphology	J:49903
	decreased body size	J:49903
	rib bifurcation	J:49903
	rib fusion	J:49903
Mesp2^tm4Ysa/Mesp2^tm4Ysa Psen1^tm1Shs/Psen1^tm1Shs involves: C57BL/6 * CBA	abnormal vertebral arch morphology	J:78989
Mesp2^{tm5(Notch1)Ysa}/Mesp2^{tm5(Notch1)Ysa} involves: C57BL/6 * CBA	abnormal vertebral arch morphology	J:78989
Mesp2^{tm5(Notch1)Ysa}/Mesp2^{tm5(Notch1)Ysa} Psen1^tm1Shs/Psen1^tm1Shs involves: C57BL/6 * CBA	abnormal vertebral arch morphology	J:78989
Mesp2^{tm7(mespb)Ysa}/Mesp2^{tm7(mespb)Ysa} involves: C57BL/6 * CBA	abnormal rostral-caudal patterning of the somites	J:75945
	abnormal somite border morphology	J:75945
	abnormal somite development	J:75945
	rib fusion	J:75945
	vertebral fusion	J:75945
Mesp2^{tm7.1(mespb)Ysa}/Mesp2^{tm7.1(mespb)Ysa} involves: C57BL/6 * CBA	kinked tail	J:75945
	normal mortality/aging	J:75945
Mesp2^{tm13.1(cre/Esr1)Ysa}/Mesp2^{tm17.1(VP16/Rbpj)Ysa} involves: C57BL/6 CBA	fusion of vertebral arches	J:167045
Mesp2^{tm15.1(Lfng)Ysa}/Mesp2^{tm15.1(Lfng)Ysa} Not Specified	abnormal somite development	J:159983
Mesp2^{tm16.1(Rbpj)Ysa}/Mesp2^{tm16.1(Rbpj)Ysa} involves: C57BL/6 * CBA	normal embryo phenotype	J:167045
	normal skeleton phenotype	J:167045
Mesp2^{tm17.1(VP16/Rbpj)Ysa}/Mesp2⁺ involves: C57BL/6 * CBA	normal skeleton phenotype	J:167045
Mesp2^{tm17.1(VP16/Rbpj)Ysa}/Mesp2^{tm17.1(VP16/Rbpj)Ysa} involves: C57BL/6 * CBA	abnormal rostral-caudal patterning of the somites	J:167045
	abnormal vertebrae morphology	J:167045
	vertebral fusion	J:167045

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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