Kif5a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Kif5a
kinesin family member 5A
MGI:109564

29 phenotypes from 5 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Kif5a^tm1.1Noh/Kif5a^tm1.1Noh B6.129S6-Kif5a^tm1.1Noh	neonatal lethality, complete penetrance	J:197666
Kif5a^tm1.1Noh/Kif5a^tm1.2Noh involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * CBA	no abnormal phenotype detected	J:197666
Kif5a^tm1.2Noh/Kif5a^tm1.2Noh Tg(Syn1-cre)671Jxm/0 involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * CBA	abnormal GABA-mediated receptor currents	J:197666
	decreased miniature inhibitory postsynaptic current amplitude	J:197666
	normal nervous system phenotype	J:197666
	postnatal growth retardation	J:197666
	postnatal lethality, complete penetrance	J:197666
	seizures	J:197666
Kif5a^{tm1b(EUCOMM)Wtsi}/Kif5a⁺ C57BL/6N-Kif5a^{tm1b(EUCOMM)Wtsi}/J	abnormal auditory brainstem response	J:211773
	impaired pupillary reflex	J:211773
Kif5a^{tm1b(EUCOMM)Wtsi}/Kif5a^{tm1b(EUCOMM)Wtsi} C57BL/6N-Kif5a^{tm1b(EUCOMM)Wtsi}/J	cyanosis	J:211773
	preweaning lethality, complete penetrance	J:211773
	unresponsive to tactile stimuli	J:211773
Kif5a^tm1Gsn/Kif5a^tm1Gsn involves: 129S1/Sv * 129X1/SvJ	abnormal vesicle-mediated transport	J:170887
Kif5a^tm1Gsn/Kif5a^tm1Gsn involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal breathing pattern	J:82911
	abnormal motor neuron morphology	J:82911
	atelectasis	J:82911
	cyanosis	J:82911
	neonatal lethality, complete penetrance	J:82911
	normal nervous system phenotype	J:82911
Kif5a^tm1Gsn/Kif5a^tm2Gsn Tg(Syn1-cre)671Jxm/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA	abnormal axonal transport	J:82911
	abnormal posture	J:82911
	abnormal protein level	J:82911
	axon degeneration	J:82911
	decreased body size	J:82911
	decreased body weight	J:82911
	hindlimb paralysis	J:82911
	impaired coordination	J:82911
	lethality at weaning, incomplete penetrance	J:82911
	premature death	J:82911
	sporadic seizures	J:82911
	tremors	J:82911

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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