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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Sftpc
surfactant associated protein C
MGI:109517
10 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Krastm4Tyj/Kras+
Sftpctm1(cre/ERT2)Blh/Sftpc+
Trp53tm5Tyj/Trp53+
involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 		abnormal pulmonary alveolus morphology J:182218
increased adenocarcinoma incidence J:182218
increased lung adenoma incidence J:182218
premature death J:182218
Krastm4Tyj/Kras+
Sftpctm1.1(cre/ERT2)Ptch/Sftpc+
involves: 129P2/OlaHsd * C57BL/6 * FVB 		increased lung adenoma incidence J:195738
Krastm4Tyj/Kras+
Sftpctm1.1(cre/ERT2)Ptch/Sftpc+
Trp53tm1Brn/Trp53tm1Brn
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB 		decreased tumor-free survival time J:195738
increased lung adenocarcinoma incidence J:195738
increased lung adenoma incidence J:195738
increased type II pneumocyte number J:195738
Mettm1Sst/Mettm1Sst
Sftpctm1(cre/ERT2,rtTA)Hap/Sftpc+
involves: 129 * 129P2/OlaHsd * C57BL/6 * FVB/N 		abnormal pulmonary alveolus morphology J:264185
emphysema J:264185
overexpanded pulmonary alveolus J:264185
Ptpratm1c(EUCOMM)Hmgu/Ptpratm1c(EUCOMM)Hmgu
Sftpctm1(cre/ERT2)Blh/Sftpc+
involves: 129S6/SvEvTac * C57BL/6N 		normal homeostasis/metabolism phenotype J:300194
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory