About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Cacna1a
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
MGI:109482
15 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Cacna1atg/Cacna1atg
Tg(Pcp2-TAg)4Horr/0
B6J.Cg-Cacna1atg Tg(Pcp2-TAg)4Horr 		ataxia J:233263
decreased Purkinje cell number J:233263
Cacna1atm1(CACNA1A)Ttan/Cacna1a+
involves: 129S4/SvJae 		impaired coordination J:123243
Cacna1atm1(CACNA1A)Ttan/Cacna1atm1(CACNA1A)Ttan
involves: 129S4/SvJae 		ataxia J:123243
dystonia J:123243
lethality at weaning, complete penetrance J:123243
Cacna1atm1.1(CACNA1A)Ttan/Cacna1atm1.1(CACNA1A)Ttan
involves: 129S4/SvJae * C57BL/6 * C57BL/6J * SJL 		ataxia J:123243
dystonia J:123243
lethality at weaning, complete penetrance J:123243
Cacna1atm1.1Kewa/Cacna1atm1.1Kewa
B6.Cg-Cacna1atm1.1Kewa 		no abnormal phenotype detected J:190729
Cacna1atm2.1Kewa/Cacna1a+
B6.Cg-Cacna1atm2.1Kewa 		abnormal motor coordination/balance J:190729
ataxia J:190729
Purkinje cell degeneration J:190729
Cacna1atm2.1Kewa/Cacna1atm2.1Kewa
B6.Cg-Cacna1atm2.1Kewa 		abnormal gait J:190729
abnormal motor coordination/balance J:190729
abnormal nervous system electrophysiology J:190729
abnormal Purkinje cell dendrite morphology J:190729
abnormal Purkinje cell mitochondrial morphology J:190729
abnormal Purkinje cell morphology J:190729
ataxia J:190729
decreased Purkinje cell size J:190729
Purkinje cell degeneration J:190729
short stride length J:190729
Cacna1atm2.1Kewa/Cacna1atm2.1Kewa
Ctsbtm1Jde/Ctsb+
involves: 129P2/OlaHsd * C57BL/6 		abnormal motor coordination/balance J:190729
Cacna1atm2.1Kewa/Cacna1atm2.1Kewa
Ctsbtm1Jde/Ctsbtm1Jde
involves: 129P2/OlaHsd * C57BL/6 		abnormal motor coordination/balance J:190729
abnormal Purkinje cell morphology J:190729
Purkinje cell degeneration J:190729
Cacna1atm3Hzo/Cacna1atm3Hzo
Ctsbtm1Jde/Ctsbtm1Jde
involves: 129P2/OlaHsd * 129S/SvEv 		Purkinje cell degeneration J:190729
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory