About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Atf2
activating transcription factor 2
MGI:109349
60 phenotypes from 6 alleles in 8 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Atf2tm1b(EUCOMM)Hmgu/Atf2+
C57BL/6N-Atf2tm1b(EUCOMM)Hmgu/Ccpcz 		abnormal heart morphology J:211773
abnormal kidney morphology J:211773
abnormal skin morphology J:211773
abnormal spleen morphology J:211773
abnormal testis morphology J:211773
abnormal urinary bladder morphology J:211773
decreased body weight J:211773
decreased circulating chloride level J:211773
decreased mean platelet volume J:211773
decreased thigmotaxis J:211773
enlarged heart J:211773
increased blood urea nitrogen level J:211773
increased circulating potassium level J:211773
increased fasting circulating glucose level J:211773
increased lung elastance J:211773
small testis J:211773
Atf2tm1Glm/Atf2+
involves: 129S2/SvPas 		postnatal lethality J:30611
Atf2tm1Glm/Atf2tm1Glm
C.Cg-Atf2tm1Glm 		abnormal cytokine secretion J:67176
decreased body weight J:67176
normal immune system phenotype J:67176
increased susceptibility to endotoxin shock J:67176
increased susceptibility to Herpesvirales infection J:67176
increased susceptibility to Picornaviridae infection J:67176
Atf2tm1Glm/Atf2tm1Glm
involves: 129S2/SvPas 		abnormal chondrocyte morphology J:30611
abnormal long bone epiphyseal plate morphology J:30611
abnormal utricular macula morphology J:30611
abnormal vestibular ganglion morphology J:30611
abnormal vestibular saccular macula morphology J:30611
ataxia J:30611
chondrodystrophy J:30611
decreased body weight J:30611
decreased brain size J:30611
decreased long bone epiphyseal plate size J:30611
decreased otolith number J:30611
decreased Purkinje cell number J:30611
decreased vestibular hair cell number J:30611
decreased vestibular hair cell stereocilia number J:30611
disorganized long bone epiphyseal plate J:30611
ectopic Purkinje cell J:30611
enlarged brain ventricles J:30611
eye inflammation J:30611
head shaking J:30611
head tossing J:30611
hyperactivity J:30611
impaired hearing J:30611
impaired limb coordination J:30611
increased susceptibility to bacterial infection J:30611
postnatal lethality, incomplete penetrance J:30611
proportional dwarf J:30611
rhizomelic limb J:30611
tremors J:30611
Atf2tm1Glm/Atf2tm1Sis
involves: 129S2/SvPas * C57BL/6 * CBA 		neonatal lethality, complete penetrance J:55657
respiratory failure J:55657
Atf2tm1Nicj/Atf2tm1Nicj
B6.129P2-Atf2tm1Nicj 		cyanosis J:123909
neonatal lethality, complete penetrance J:123909
Atf2tm1Sis/Atf2tm1Sis
either: (involves: C57BL/6 * CBA) or (involves: BALB/c * C57BL/6 * CBA) or (involves: C57BL/6 * CBA * ICR) 		abnormal lung morphology J:55657
abnormal placenta labyrinth morphology J:55657
abnormal placenta vasculature J:55657
cyanosis J:55657
hypoxia J:55657
neonatal lethality, complete penetrance J:55657
respiratory failure J:55657
Atf2tm2Nicj/Atf2tm2Nicj
B6.129P2-Atf2tm2Nicj 		cyanosis J:123909
neonatal lethality, complete penetrance J:123909
Atf2tm3Nicj/Atf2tm3Nicj
involves: C57BL/6 * FVB/N 		no abnormal phenotype detected J:131564
Atf2tm3Nicj/Atf2tm3Nicj
Tg(KRT14-cre)1Efu/?
involves: C57BL/6 * FVB/N 		epidermal hyperplasia J:131564
increased skin papilloma incidence J:131564
thick epidermis J:131564
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory